pleckstrin homology domain containing, family B (evectins) member 1

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Synonym

PLEKHB1, PHRET1, PH domain-containing protein in retina 1, PHR1, KPL1, Pleckstrin homology domain retinal protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:956.40 cerebellum:1259.40 brain stem:- corpus callosum/glia:3236.90 pineal gland:2225.20 peripheral nerve:- spine:- retina:237.30 eye:511.30 artery/aorta:- vein:- lymphnode:- peripheral blood:18.20 spleen:- thymus:38.70 bone marrow:19.70 adipose:- bone:25.60 skin:4.80
GeneChip cerebrum:10.36 cerebellum:8.65 brain stem:10.72 corpus callosum/glia:11.32 pineal gland:- peripheral nerve:9.28 spine:11.74 retina:- eye:- artery/aorta:5.48 vein:5.01 lymphnode:5.25 peripheral blood:- spleen:4.36 thymus:4.82 bone marrow:4.52 adipose:4.44 bone:- skin:4.32
CAGE cerebrum:6.32 cerebellum:- brain stem:6.86 corpus callosum/glia:7.52 pineal gland:6.42 peripheral nerve:- spine:7.16 retina:- eye:- artery/aorta:3.01 vein:2.75 lymphnode:2.78 peripheral blood:- spleen:1.85 thymus:1.71 bone marrow:- adipose:1.12 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:22.50 ovary:- testis:43.30 heart:38.30 muscle:- esophagus:- stomach:63.70 intestine:97.20 colon:67.80     liver/hepato:-        lung:39.10    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:818.70 adrenal gland:50.80 pancreas:133.40 breast:55.80 salivary:-
GeneChip uterus:4.43 placenta:3.98 prostate:5.50 ovary:5.18 testis:5.77 heart:5.20 muscle:5.09 esophagus:4.60 stomach:5.94 intestine:6.05 colon:6.14 liver/hepato:3.92 lung:5.25 bladder:- kidney:5.57 pituitary:8.44 thyroid/parathyroid:6.76 adrenal gland:4.22 pancreas:5.57 breast:5.04 salivary:7.74
CAGE uterus:1.84 placenta:0.59 prostate:2.68 ovary:2.34 testis:2.49 heart:2.22 muscle:1.35 esophagus:3.19 stomach:- intestine:2.69 colon:2.55     liver/hepato:0.78    lung:2.74 bladder:2.10 kidney:2.58 pituitary:5.23 thyroid/parathyroid:3.29 adrenal gland:- pancreas:3.16 breast:2.19 salivary:4.97
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0        lung:0.00    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_021200
Gene ID 58473
Unigene ID Hs.445489
Probe set ID 209504_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000021300
GTEx ID ENSG00000021300

Orthologous Gene

Mouse[7]  NM_001163182, NM_001163183, NM_001163184, NM_001163185, NM_001163186, NM_001163187, NM_013746
Rat[1]  NM_172033, NM_001163183, NM_001163184, NM_001163185, NM_001163186, NM_001163187, NM_013746

Chromosomal Region

11q13.4  [73,357,223  -  73,373,864]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

10585447
10923244
12477932
14702039
15489334
15761153
19913121
20301200
20308990
20628086
23275563
24840802

Gene Ontology  (GO ID)

Biological Process

GO:0007275  multicellular organismal development
GO:0007602  phototransduction
GO:0045595  regulation of cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0016021  integral to membrane

Molecular Function

GO:0005543  phospholipid binding
GO:0008022  protein C-terminus binding
GO:0042803  protein homodimerization activity
GO:0004871  signal transducer activity