CREB/ATF bZIP transcription factor

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Synonym

HCF-binding transcription factor Zhangfei, ZF

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:39.10 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:153.40 spine:112.30 retina:- eye:141 artery/aorta:60 vein:- lymphnode:444.90 peripheral blood:- spleen:- thymus:64.40 bone marrow:137.80 adipose:80.70 bone:12.80 skin:28.80
GeneChip cerebrum:4.55 cerebellum:4.67 brain stem:4.54 corpus callosum/glia:4.98 pineal gland:- peripheral nerve:5.01 spine:5.27 retina:- eye:- artery/aorta:5.05 vein:4.80 lymphnode:5.83 peripheral blood:- spleen:6.29 thymus:7.16 bone marrow:5.35 adipose:5.12 bone:- skin:5.36
CAGE cerebrum:4.04 cerebellum:- brain stem:4.20 corpus callosum/glia:4.15 pineal gland:3.73 peripheral nerve:- spine:4.17 retina:- eye:- artery/aorta:4.22 vein:3.86 lymphnode:3.81 peripheral blood:- spleen:3.51 thymus:3.86 bone marrow:- adipose:3.38 bone:- skin:-
RNA-seq cerebrum:2.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.56 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.68 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:154.90 placenta:134.80 prostate:45.10 ovary:74.50 testis:69.20 heart:191.60 muscle:- esophagus:- stomach:- intestine:- colon:542.70     liver/hepato:84.40        lung:78.20    bladder:- kidney:197.50 pituitary:- thyroid/parathyroid:163.70 adrenal gland:152.40 pancreas:53.30 breast:83.60 salivary:-
GeneChip uterus:5.61 placenta:6 prostate:6.26 ovary:5.30 testis:4.92 heart:4.62 muscle:4.46 esophagus:4.70 stomach:5.44 intestine:5.23 colon:4.61 liver/hepato:5.04 lung:5.03 bladder:- kidney:4.76 pituitary:4.99 thyroid/parathyroid:5.58 adrenal gland:5.23 pancreas:5.01 breast:5.54 salivary:5.04
CAGE uterus:4.14 placenta:3.60 prostate:3.77 ovary:3.71 testis:3.51 heart:3.31 muscle:3.22 esophagus:3.44 stomach:- intestine:3.65 colon:3.88     liver/hepato:3.00    lung:3.94 bladder:3.82 kidney:3.28 pituitary:4.20 thyroid/parathyroid:3.56 adrenal gland:- pancreas:3.85 breast:3.80 salivary:3.87
RNA-seq uterus:- placenta:- prostate:3.25 ovary:3.24 testis:2.53 heart:1.91 muscle:1.83 esophagus:- stomach:- intestine:- colon:2.69     liver/hepato:2.34        lung:3.50    bladder:- kidney:2.39 pituitary:- thyroid/parathyroid:3.23 adrenal gland:2.82 pancreas:- breast:2.61 salivary:-

Gene Information

IDs

Refseq ID NM_001039618
Gene ID 58487
Unigene ID Hs.535319
Probe set ID 202979_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137504
GTEx ID ENSG00000137504

Orthologous Gene

Mouse[2]  NM_145151
Rat[1]  NM_001106279

Chromosomal Region

11q14.1  [85,370,752  -  85,393,951]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10871379
12235138
12477932
15146197
15231748
15489334
15705566
16282471
16343488
16344560
18657049
18719857
19016376
19322201
19690166
21603654
21906983
21994947
22134986
22707059
22798206
22983008
23661758
24155933
24200963
24265317

Gene Ontology  (GO ID)

Biological Process

GO:0045814  negative regulation of gene expression, epigenetic
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0051090  regulation of transcription factor activity
GO:0009615  response to virus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity