myosin, light chain 7, regulatory

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Synonym

Myosin regulatory light chain 2, atrial isoform, MYL2A, myosin, light chain 7, regulatory, MLC-2a, MYL7, MYLC2A, light polypeptide 7, MLC2a, Myosin light chain 2a, Myosin regulatory light chain 7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:80.70 bone:12.80 skin:-
GeneChip cerebrum:5 cerebellum:5.02 brain stem:5.06 corpus callosum/glia:4.79 pineal gland:- peripheral nerve:4.63 spine:4.68 retina:- eye:- artery/aorta:5.76 vein:8.58 lymphnode:4.74 peripheral blood:- spleen:4.53 thymus:4.52 bone marrow:4.89 adipose:4.78 bone:- skin:4.92
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.34 vein:3.40 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.03 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.24 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.08 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:- heart:4508.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:10.60        lung:136.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.82 placenta:4.59 prostate:4.65 ovary:4.89 testis:4.54 heart:10.21 muscle:5.51 esophagus:4.95 stomach:4.77 intestine:5.10 colon:5.09 liver/hepato:4.78 lung:4.64 bladder:- kidney:4.81 pituitary:5.11 thyroid/parathyroid:4.39 adrenal gland:5.93 pancreas:5.18 breast:4.70 salivary:4.90
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0.07 heart:6.06 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.08 ovary:0.23 testis:0.12 heart:8.79 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.07        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0.11 salivary:-

Gene Information

IDs

Refseq ID NM_021223
Gene ID 58498
Unigene ID Hs.75636
Probe set ID 219942_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000106631
GTEx ID ENSG00000106631

Orthologous Gene

Mouse[1]  NM_022879
Rat[2]  NM_001106017

Chromosomal Region

7p13  [44,178,463  -  44,180,931]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR018249  EF-HAND 2

Link to Pubmed  (Pubmed ID)

1429676
8207020
12083776
12477932
12757876
12847096
15489334
15621049
15735645
18718080
19794400

Gene Ontology  (GO ID)

Biological Process

GO:0030048  actin filament-based movement
GO:0006939  smooth muscle contraction

Cellular Component

GO:0031672  A band
GO:0043197  dendritic spine
GO:0016459  myosin complex

Molecular Function

GO:0042623  ATPase activity, coupled
GO:0005509  calcium ion binding
GO:0000146  microfilament motor activity