RAB5B, member RAS oncogene family

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Synonym

Ras-related protein Rab-5B, RAB5B, RAB5B, member RAS oncogene family

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:189.60 cerebellum:176.30 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:153.40 spine:336.90 retina:- eye:82.30 artery/aorta:89.90 vein:199.90 lymphnode:40.40 peripheral blood:91.10 spleen:132.30 thymus:154.60 bone marrow:98.40 adipose:80.70 bone:166.30 skin:129.60
GeneChip cerebrum:8.51 cerebellum:8.51 brain stem:8.43 corpus callosum/glia:8.96 pineal gland:- peripheral nerve:8.79 spine:8.99 retina:- eye:- artery/aorta:8.39 vein:8.25 lymphnode:8.23 peripheral blood:- spleen:8.32 thymus:7.99 bone marrow:8.42 adipose:8.13 bone:- skin:8.24
CAGE cerebrum:4.96 cerebellum:- brain stem:5.28 corpus callosum/glia:5.63 pineal gland:4.56 peripheral nerve:- spine:4.81 retina:- eye:- artery/aorta:4.66 vein:4.32 lymphnode:4.27 peripheral blood:- spleen:4.31 thymus:4.07 bone marrow:- adipose:4.65 bone:- skin:-
RNA-seq cerebrum:2.29 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.44 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:153 prostate:45.10 ovary:111.80 testis:103.80 heart:76.60 muscle:- esophagus:- stomach:42.50 intestine:97.20 colon:127.20     liver/hepato:10.60        lung:122.20    bladder:125.60 kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:62.20 breast:148.70 salivary:-
GeneChip uterus:8.43 placenta:8.35 prostate:8.40 ovary:8.53 testis:8.30 heart:8.05 muscle:7.76 esophagus:8.99 stomach:8.31 intestine:7.86 colon:8.41 liver/hepato:7.87 lung:8.56 bladder:- kidney:8.33 pituitary:8 thyroid/parathyroid:8.63 adrenal gland:8.22 pancreas:7.30 breast:8.69 salivary:8.23
CAGE uterus:4.92 placenta:4.73 prostate:4.80 ovary:4.71 testis:4.69 heart:4.33 muscle:4.68 esophagus:4.93 stomach:- intestine:4.69 colon:4.33     liver/hepato:4.31    lung:4.53 bladder:4.78 kidney:4.60 pituitary:4.57 thyroid/parathyroid:4.67 adrenal gland:- pancreas:4.19 breast:4.03 salivary:4.88
RNA-seq uterus:- placenta:- prostate:0.20 ovary:3.17 testis:3.38 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:2.60     liver/hepato:0.39        lung:0.21    bladder:- kidney:1.04 pituitary:- thyroid/parathyroid:2.29 adrenal gland:1.96 pancreas:- breast:2.37 salivary:-

Gene Information

IDs

Refseq ID NM_002868
Gene ID 5869
Unigene ID Hs.567328
Probe set ID 201276_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000111540
GTEx ID ENSG00000111540

Orthologous Gene

Mouse[1]  NM_177411
Rat[1]  NM_001079936

Chromosomal Region

12q13.2  [56,367,697  -  56,388,490]

Gene Family (Interpro ID)

IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

1541686
7789520
8666383
9918381
10329441
10403367
10491193
11076863
11230166
11256614
11703925
11733506
12477932
12493736
12535645
12972505
15326289
15489334
15489336
16344560
16381901
16923123
17081065
17927960
18198356
18445495
19322201
19717423
19723633
20526340
21139048
21988832
22885925
22939629
22951725
23000965
24106282
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0007032  endosome organization
GO:0006184  GTP catabolic process
GO:0015031  protein transport
GO:0030100  regulation of endocytosis
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0031901  early endosome membrane
GO:0030139  endocytic vesicle
GO:0005768  endosome
GO:0005622  intracellular
GO:0042470  melanosome
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding
GO:0030742  GTP-dependent protein binding
GO:0003924  GTPase activity
GO:0005515  protein binding