RAB5C, member RAS oncogene family

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Synonym

RAB5CL, RAB5C, RABL, RAB5C, member RAS oncogene family, RAB5L, MGC138857, MGC117217, Ras-related protein Rab-5C, L1880

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.59 cerebellum:7.37 brain stem:7.51 corpus callosum/glia:7.65 pineal gland:- peripheral nerve:7.40 spine:7.58 retina:- eye:- artery/aorta:7.48 vein:7.76 lymphnode:7.30 peripheral blood:- spleen:7.42 thymus:6.90 bone marrow:7.59 adipose:7.59 bone:- skin:7.20
CAGE cerebrum:4.45 cerebellum:- brain stem:4.64 corpus callosum/glia:4.86 pineal gland:3.71 peripheral nerve:- spine:4.12 retina:- eye:- artery/aorta:4.45 vein:4.42 lymphnode:4.57 peripheral blood:- spleen:4.79 thymus:4.10 bone marrow:- adipose:4.61 bone:- skin:-
RNA-seq cerebrum:5.67 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.97 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.43 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:7.45 placenta:7.01 prostate:7 ovary:7.60 testis:7.06 heart:7.30 muscle:6.25 esophagus:7.51 stomach:7.65 intestine:7.45 colon:7.90 liver/hepato:7.18 lung:7.59 bladder:- kidney:8.16 pituitary:7.01 thyroid/parathyroid:7.72 adrenal gland:7.26 pancreas:7.57 breast:7.78 salivary:7.17
CAGE uterus:4.37 placenta:4.55 prostate:4.38 ovary:4.43 testis:4.31 heart:4.06 muscle:3.54 esophagus:4.38 stomach:- intestine:4.78 colon:4.43     liver/hepato:4.88    lung:4.61 bladder:4.31 kidney:5.10 pituitary:3.56 thyroid/parathyroid:4.81 adrenal gland:- pancreas:4.03 breast:4.19 salivary:4.37
RNA-seq uterus:- placenta:- prostate:5.95 ovary:5.76 testis:5.77 heart:4.15 muscle:4.18 esophagus:- stomach:- intestine:- colon:5.60     liver/hepato:5.44        lung:6.33    bladder:- kidney:6.41 pituitary:- thyroid/parathyroid:6.36 adrenal gland:6.15 pancreas:- breast:5.75 salivary:-

Gene Information

IDs

Refseq ID NM_004583
Gene ID 5878
Unigene ID Hs.650382
Probe set ID 201140_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000108774
GTEx ID ENSG00000108774

Orthologous Gene

Mouse[1]  NM_024456
Rat [0]  

Chromosomal Region

17q21.2  [40,276,994  -  40,307,035]

Gene Family (Interpro ID)

IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

7951316
8646882
9852039
10329441
10768959
11733506
12477932
12493736
12972505
14741744
15342556
16923123
17081065
17255364
17353931
17897319
18029348
19056867
19738201
20360068
21139048
21319273
21832049
21890473
21906983
21963094
21987572
22505724
22623428
22734003
22939629
23000965
23125841
24332808
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007032  endosome organization
GO:0006184  GTP catabolic process
GO:0015031  protein transport
GO:0030100  regulation of endocytosis
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0031901  early endosome membrane
GO:0030139  endocytic vesicle
GO:0005811  lipid particle
GO:0042470  melanosome
GO:0005886  plasma membrane

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding
GO:0003924  GTPase activity