RAP1A, member of RAS oncogene family

Synonym

Ras-related protein Rap-1A precursor, Rap 1a, Rap 1A, RAP1, Rap1A, C21KG, RAP 1A, RAP 1a, KREV-1, G-22K, GTP-binding protein smg-p21A, RAP1A, KREV1, Ras-related protein Krev-1, RAP1A, member of RAS oncogene family, SMGP21

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:51

cerebellum:37.80

brain stem:-

corpus callosum/glia:-

pineal gland:148.30

peripheral nerve:92

spine:224.60

retina:-

eye:47

artery/aorta:359.70

vein:133.30

lymphnode:121.30

peripheral blood:91.10

spleen:75.60

thymus:38.70

bone marrow:118.10

adipose:40.30

bone:51.20

skin:67.20

GeneChip

cerebrum:7.67

cerebellum:7

brain stem:8.06

corpus callosum/glia:8.33

pineal gland:-

peripheral nerve:7.84

spine:8.41

retina:-

eye:-

artery/aorta:8.41

vein:9.09

lymphnode:8.60

peripheral blood:-

spleen:8.53

thymus:8.63

bone marrow:8.58

adipose:8.37

bone:-

skin:8.22

CAGE

cerebrum:3.61

cerebellum:-

brain stem:4.05

corpus callosum/glia:4.11

pineal gland:3.55

peripheral nerve:-

spine:4.12

retina:-

eye:-

artery/aorta:4.12

vein:3.95

lymphnode:4.01

peripheral blood:-

spleen:4.26

thymus:3.85

bone marrow:-

adipose:4.08

bone:-

skin:-

RNA-seq

cerebrum:2.14

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.60

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.41

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:63.80

placenta:134.80

prostate:67.60

ovary:37.30

testis:64.90

heart:25.50

muscle:60.30

esophagus:-

stomach:-

intestine:32.40

colon:42.40

liver/hepato:73.90

lung:83.10

bladder:-

kidney:93.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:151.10

breast:27.90

salivary:-

GeneChip

uterus:8.31

placenta:7.87

prostate:8.84

ovary:8

testis:6.68

heart:8.42

muscle:7.93

esophagus:8.31

stomach:8.59

intestine:8.52

colon:8.50

liver/hepato:7.85

lung:8.46

bladder:-

kidney:7.90

pituitary:7.62

thyroid/parathyroid:8.12

adrenal gland:8.17

pancreas:7.66

breast:8.18

salivary:8.41

CAGE

uterus:4.16

placenta:3.66

prostate:4.34

ovary:3.62

testis:3.08

heart:4.23

muscle:3.95

esophagus:4.54

stomach:-

intestine:4.07

colon:4.12

liver/hepato:3.72

lung:4.17

bladder:5.06

kidney:3.87

pituitary:3.95

thyroid/parathyroid:3.87

adrenal gland:-

pancreas:2.90

breast:3.92

salivary:3.81

RNA-seq

uterus:-

placenta:-

prostate:4.15

ovary:1.84

testis:2.05

heart:2.62

muscle:3.04

esophagus:-

stomach:-

intestine:-

colon:2.86

liver/hepato:0.05

lung:1.89

bladder:-

kidney:1.36

pituitary:-

thyroid/parathyroid:2.82

adrenal gland:2.52

pancreas:-

breast:1.53

salivary:-

IDs

Refseq ID	NM_001010935
Gene ID	5906
Unigene ID	Hs.190334
Probe set ID	202362_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000116473
GTEx ID	ENSG00000116473

Orthologous Gene

Mouse[2]	NM_145541
Rat [0]

Chromosomal Region

1p13.2 [112,084,840 - 112,259,313]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002041	Ran GTPase
IPR013753	Ras
IPR001806	Ras GTPase
IPR020849	Ras small GTPase
IPR003579	Ras small GTPase, Rab type
IPR005225	Small GTP-binding protein
IPR020851	Small GTPase
IPR003578	Small GTPase, Rho type

Gene Ontology (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0007596	blood coagulation
GO:0006112	energy reserve metabolic process
GO:0048011	nerve growth factor receptor signaling pathway
GO:0030168	platelet activation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0010976	positive regulation of neuron projection development
GO:0045860	positive regulation of protein kinase activity
GO:0032854	positive regulation of Rap GTPase activity
GO:0015031	protein transport
GO:0050796	regulation of insulin secretion
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction

Cellular Component

GO:0030054	cell junction
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005769	early endosome
GO:0032045	guanyl-nucleotide exchange factor complex
GO:0005770	late endosome
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0008565	protein transporter activity
GO:0017034	Rap guanyl-nucleotide exchange factor activity
GO:0017016	Ras GTPase binding

RAP1A, member of RAS oncogene family

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function