retinoic acid receptor, gamma

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:- skin:-
GeneChip cerebrum:6.81 cerebellum:6.73 brain stem:6.85 corpus callosum/glia:6.60 pineal gland:- peripheral nerve:6.70 spine:6.56 retina:- eye:- artery/aorta:6.81 vein:7.10 lymphnode:6.87 peripheral blood:- spleen:6.53 thymus:6.33 bone marrow:6.92 adipose:6.95 bone:- skin:7.11
CAGE cerebrum:1.25 cerebellum:- brain stem:1.14 corpus callosum/glia:1.17 pineal gland:1.27 peripheral nerve:- spine:0.65 retina:- eye:- artery/aorta:3.02 vein:2.69 lymphnode:2.92 peripheral blood:- spleen:1.93 thymus:1.24 bone marrow:- adipose:1.93 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.87 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.83 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:22.50 ovary:- testis:26 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:10.60        lung:29.30    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.79 placenta:6.64 prostate:6.58 ovary:6.76 testis:6.40 heart:6.89 muscle:6.93 esophagus:7.38 stomach:6.71 intestine:6.82 colon:7.01 liver/hepato:6.75 lung:6.63 bladder:- kidney:6.74 pituitary:6.83 thyroid/parathyroid:6.61 adrenal gland:6.83 pancreas:6.92 breast:6.76 salivary:6.98
CAGE uterus:3.39 placenta:1.92 prostate:2.82 ovary:2.82 testis:1.74 heart:2.09 muscle:0.66 esophagus:4.23 stomach:- intestine:1.17 colon:2.23     liver/hepato:1.12    lung:2.38 bladder:2.72 kidney:1.67 pituitary:0.87 thyroid/parathyroid:2.12 adrenal gland:- pancreas:1.42 breast:2.91 salivary:2.22
RNA-seq uterus:- placenta:- prostate:1.75 ovary:2.22 testis:1.04 heart:0.12 muscle:0.00 esophagus:- stomach:- intestine:- colon:1.24     liver/hepato:0.20        lung:1.16    bladder:- kidney:0.37 pituitary:- thyroid/parathyroid:1.74 adrenal gland:0.59 pancreas:- breast:0.92 salivary:-

Gene Information

IDs

Refseq ID NM_000966
Gene ID 5916
Unigene ID Hs.149774
Probe set ID 204189_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000172819
GTEx ID ENSG00000172819

Orthologous Gene

Mouse[4]  NM_001042727, NM_011244
Rat[2]  NM_001135249, NM_001135250

Chromosomal Region

12q13.13  [53,604,354  -  53,626,764]

Gene Family (Interpro ID)

IPR003070  Orphan nuclear receptor
IPR003078  Retinoic acid receptor
IPR000003  Retinoid X receptor
IPR001723  Steroid hormone receptor
IPR001728  Thyroid hormone receptor
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

1310259
1318502
1320193
1655630
1849262
2157210
2157970
2172793
2546152
7501014
7685085
8301142
9083083
9491782
9501913
9852056
9865725
10318855
10336495
10428834
11641790
11855864
12189556
12220491
12399530
12477932
12554770
12665583
14603262
14657503
14691372
14705796
15383624
15489334
15604093
15635645
15734736
15839736
16344560
16456540
17195188
17252005
17325034
17363140
17574023
17943189
18438858
18484682
18685608
18816836
18845237
18996102
19345331
19350571
19416972
19416983
19563758
19732752
19902255
19913121
20133701
20346360
20387030
20420906
20602615
20628086
20634891
20857416
21178008
21254357
21401418
21923909
21988832
21990348
22362749
22901127
23000965
23518499
23798555

Gene Ontology  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0071300  cellular response to retinoic acid
GO:0048048  embryonic eye morphogenesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0010467  gene expression
GO:0003430  growth plate cartilage chondrocyte growth
GO:0070384  Harderian gland development
GO:0035264  multicellular organism growth
GO:0008285  negative regulation of cell proliferation
GO:0032331  negative regulation of chondrocyte differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0043068  positive regulation of programmed cell death
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060740  prostate gland epithelium morphogenesis
GO:0008361  regulation of cell size
GO:0031641  regulation of myelination
GO:0032526  response to retinoic acid
GO:0048384  retinoic acid receptor signaling pathway
GO:0060534  trachea cartilage development
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0016021  integral to membrane
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0003708  retinoic acid receptor activity
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding