regulatory factor X, 3 (influences HLA class II expression)

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Synonym

RFX3, MGC87155, bA32F11.1, Transcription factor RFX3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:30.80 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:17.60 artery/aorta:- vein:- lymphnode:121.30 peripheral blood:18.20 spleen:- thymus:90.20 bone marrow:98.40 adipose:- bone:12.80 skin:24
GeneChip cerebrum:3.72 cerebellum:3.69 brain stem:3.73 corpus callosum/glia:3.84 pineal gland:- peripheral nerve:3.77 spine:3.77 retina:- eye:- artery/aorta:3.81 vein:3.74 lymphnode:3.74 peripheral blood:- spleen:3.66 thymus:3.52 bone marrow:3.99 adipose:3.76 bone:- skin:3.67
CAGE cerebrum:4.31 cerebellum:- brain stem:3.67 corpus callosum/glia:3.95 pineal gland:4.61 peripheral nerve:- spine:4.67 retina:- eye:- artery/aorta:3.43 vein:3.50 lymphnode:3.61 peripheral blood:- spleen:3.63 thymus:4.24 bone marrow:- adipose:3.36 bone:- skin:-
RNA-seq cerebrum:0.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.32 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.02 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:18.20 prostate:11.30 ovary:74.50 testis:173.10 heart:25.50 muscle:40.20 esophagus:- stomach:63.70 intestine:- colon:42.40     liver/hepato:21.10        lung:48.90    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:55.80 salivary:-
GeneChip uterus:3.75 placenta:3.74 prostate:3.58 ovary:3.74 testis:3.84 heart:3.78 muscle:3.81 esophagus:3.72 stomach:3.76 intestine:3.65 colon:3.82 liver/hepato:3.68 lung:3.84 bladder:- kidney:3.76 pituitary:3.70 thyroid/parathyroid:3.61 adrenal gland:3.70 pancreas:3.93 breast:3.69 salivary:3.68
CAGE uterus:3.99 placenta:2.79 prostate:3.65 ovary:3.61 testis:3.85 heart:3.05 muscle:3.18 esophagus:2.98 stomach:- intestine:2.93 colon:3.32     liver/hepato:1.95    lung:3.88 bladder:3.58 kidney:2.90 pituitary:4.66 thyroid/parathyroid:3.26 adrenal gland:- pancreas:2.66 breast:3.69 salivary:2.43
RNA-seq uterus:- placenta:- prostate:0.33 ovary:0.40 testis:0.66 heart:0.05 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.15     liver/hepato:0.00        lung:0.41    bladder:- kidney:0.14 pituitary:- thyroid/parathyroid:0.67 adrenal gland:0.62 pancreas:- breast:0.15 salivary:-

Gene Information

IDs

Refseq ID NM_002919
Gene ID 5991
Unigene ID Hs.136829
Probe set ID 207234_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000080298
GTEx ID ENSG00000080298

Orthologous Gene

Mouse[4]  NM_001166414, NM_011265
Rat[1]  NM_001012172, NM_011265

Chromosomal Region

9p24.2  [3,218,297  -  3,526,004]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8289803
8600444
8889548
10330134
11682486
12411430
12477932
14702039
15024578
15164053
15489334
16189514
16344560
19671664
20211142
21532573
22415835
23822649
24058526

Gene Ontology  (GO ID)

Biological Process

GO:0048469  cell maturation
GO:0060285  ciliary cell motility
GO:0042384  cilium assembly
GO:0060287  cilium movement involved in determination of left/right asymmetry
GO:0031018  endocrine pancreas development
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0050796  regulation of insulin secretion
GO:0006355  regulation of transcription, DNA-dependent

Cellular Component

GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0003700  transcription factor activity