retinal G protein coupled receptor

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Synonym

RPE-retinal G protein-coupled receptor, RGR, retinal G protein coupled receptor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:39.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:112.30 retina:- eye:5.90 artery/aorta:30 vein:- lymphnode:20.20 peripheral blood:- spleen:18.90 thymus:25.80 bone marrow:19.70 adipose:40.30 bone:25.60 skin:4.80
GeneChip cerebrum:5 cerebellum:4.87 brain stem:5.11 corpus callosum/glia:4.75 pineal gland:- peripheral nerve:4.59 spine:4.65 retina:- eye:- artery/aorta:5 vein:5.01 lymphnode:4.70 peripheral blood:- spleen:4.56 thymus:4.39 bone marrow:4.95 adipose:4.93 bone:- skin:4.89
CAGE cerebrum:2.23 cerebellum:- brain stem:0.37 corpus callosum/glia:1.73 pineal gland:1.80 peripheral nerve:- spine:0.42 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.45 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.12 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:14.60 prostate:22.50 ovary:111.80 testis:13 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:17     liver/hepato:105.60        lung:19.60    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:9.30 salivary:-
GeneChip uterus:4.63 placenta:4.65 prostate:4.49 ovary:4.63 testis:4.60 heart:4.98 muscle:5.04 esophagus:4.75 stomach:4.74 intestine:4.76 colon:4.95 liver/hepato:4.91 lung:4.72 bladder:- kidney:4.87 pituitary:4.91 thyroid/parathyroid:4.65 adrenal gland:4.82 pancreas:5.07 breast:4.53 salivary:4.85
CAGE uterus:0.04 placenta:0 prostate:0 ovary:0.07 testis:0.04 heart:0.14 muscle:0.05 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0.26 thyroid/parathyroid:0.17 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.70 ovary:0 testis:0.00 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.07     liver/hepato:0        lung:0.05    bladder:- kidney:0.02 pituitary:- thyroid/parathyroid:0.02 adrenal gland:0 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_001012722
Gene ID 5995
Unigene ID Hs.154429
Probe set ID 207070_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000148604
GTEx ID ENSG00000148604

Orthologous Gene

Mouse[1]  NM_021340
Rat[1]  NM_001107299

Chromosomal Region

10q23.1  [86,004,809  -  86,019,716]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR001793  Retinal pigment epithelium GPCR

Link to Pubmed  (Pubmed ID)

7789419
7947717
8641686
10581022
11274198
11723126
12477932
12542842
12573668
12843338
15489334
16189514
16385451
16737970
17286855
17679941
18240029
18474598
19450444
20301590
20591486
20801516
21067480
21441953

Gene Ontology  (GO ID)

Biological Process

GO:0006935  chemotaxis
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007602  phototransduction
GO:0018298  protein-chromophore linkage
GO:0007601  visual perception

Cellular Component

GO:0005887  integral to plasma membrane

Molecular Function

GO:0004950  chemokine receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0009881  photoreceptor activity
GO:0005515  protein binding