ribosomal protein S27a

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Synonym

UBCEP1, UBA80, HUBCEP80, 40S ribosomal protein S27a, ribosomal protein S27a, CEP80, RPS27A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:69.90 cerebellum:37.80 brain stem:- corpus callosum/glia:58.30 pineal gland:296.70 peripheral nerve:30.70 spine:- retina:- eye:11.80 artery/aorta:179.90 vein:799.80 lymphnode:283.10 peripheral blood:91.10 spleen:359.20 thymus:193.30 bone marrow:196.80 adipose:161.30 bone:38.40 skin:67.20
GeneChip cerebrum:11.21 cerebellum:11.09 brain stem:11.42 corpus callosum/glia:11.18 pineal gland:- peripheral nerve:11.49 spine:11.29 retina:- eye:- artery/aorta:11.75 vein:11.55 lymphnode:12.07 peripheral blood:- spleen:11.78 thymus:12.11 bone marrow:11.43 adipose:11.83 bone:- skin:12.05
CAGE cerebrum:3.12 cerebellum:- brain stem:2.80 corpus callosum/glia:2.19 pineal gland:2.79 peripheral nerve:- spine:2.71 retina:- eye:- artery/aorta:2.76 vein:3.09 lymphnode:3.30 peripheral blood:- spleen:3.46 thymus:3.11 bone marrow:- adipose:2.84 bone:- skin:-
RNA-seq cerebrum:0.38 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:58.30 prostate:146.40 ovary:186.30 testis:51.90 heart:191.60 muscle:80.40 esophagus:685.60 stomach:63.70 intestine:97.20 colon:59.40     liver/hepato:327.20        lung:58.70    bladder:251.20 kidney:10.40 pituitary:695.90 thyroid/parathyroid:818.70 adrenal gland:101.60 pancreas:142.30 breast:55.80 salivary:-
GeneChip uterus:12.10 placenta:11.08 prostate:12.32 ovary:12.21 testis:11.31 heart:11.34 muscle:10.50 esophagus:11.49 stomach:11.66 intestine:11.51 colon:11.55 liver/hepato:11.05 lung:11.50 bladder:- kidney:11.44 pituitary:11.77 thyroid/parathyroid:11.85 adrenal gland:11.66 pancreas:11.98 breast:11.86 salivary:12.09
CAGE uterus:2.68 placenta:3.13 prostate:2.47 ovary:2.89 testis:2.97 heart:3.14 muscle:3.64 esophagus:3.07 stomach:- intestine:2.85 colon:2.85     liver/hepato:4.16    lung:2.92 bladder:2.61 kidney:3.36 pituitary:3.26 thyroid/parathyroid:3.16 adrenal gland:- pancreas:3.61 breast:2.99 salivary:2.99
RNA-seq uterus:- placenta:- prostate:0.66 ovary:0.31 testis:1.52 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.64        lung:0.00    bladder:- kidney:0.52 pituitary:- thyroid/parathyroid:0.20 adrenal gland:0.43 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001135592
Gene ID 6233
Unigene ID Hs.546292
Probe set ID 200017_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000143947
GTEx ID ENSG00000143947

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

2p16.1  [55,459,039  -  55,462,989]

Gene Family (Interpro ID)

IPR000626  Ubiquitin
IPR019956  Ubiquitin subgroup
IPR019955  Ubiquitin supergroup

Link to Pubmed  (Pubmed ID)

1370760
1657614
1660345
2537304
2538756
2581967
8125298
8706699
8722009
9582194
10772958
10882101
10995389
11031247
11231585
11285280
11733996
11875025
11931757
12477932
12588972
12609980
12787561
12791267
12960054
14702039
14755250
14764729
15029244
15039775
15143060
15146197
15189156
15231748
15276183
15489334
15647830
15721744
15761153
15883184
15936278
16009940
16169070
16189514
16196087
16344560
16997282
17207965
17304240
17620599
18655026
19061985
19199708
19471022
19738201
19850743
19946888
20473970
20639865
20972266
21139048
21145461
21163940
21252943
21319273
21561866
21693764
21832049
21853274
21890473
21906983
21963094
21987572
21988832
22053931
22108332
22145905
22174317
22505724
22623428
22716248
22863883
22939629
23000965
23246001
23398456
23455922
24244333
24399297
24457600
24583282
24680683
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0006915  apoptosis
GO:0044267  cellular protein metabolic process
GO:0071456  cellular response to hypoxia
GO:0019221  cytokine-mediated signaling pathway
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0006281  DNA repair
GO:0046788  egress of virus within host cell
GO:0016197  endosome transport
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0000082  G1/S transition of mitotic cell cycle
GO:0010467  gene expression
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0045087  innate immune response
GO:0034220  ion transmembrane transport
GO:0007254  JNK cascade
GO:0016044  membrane organization
GO:0000278  mitotic cell cycle
GO:0016071  mRNA metabolic process
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030512  negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032480  negative regulation of type I interferon production
GO:0051436  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007220  Notch receptor processing
GO:0007219  Notch signaling pathway
GO:0000184  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0070423  nucleotide-binding oligomerization domain containing signaling pathway
GO:0043065  positive regulation of apoptosis
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032481  positive regulation of type I interferon production
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0000209  protein polyubiquitination
GO:0042981  regulation of apoptosis
GO:0032479  regulation of type I interferon production
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0016070  RNA metabolic process
GO:0006614  SRP-dependent cotranslational protein targeting to membrane
GO:0051403  stress-activated MAPK cascade
GO:0050852  T cell receptor signaling pathway
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0006412  translation
GO:0006414  translational elongation
GO:0006413  translational initiation
GO:0006415  translational termination
GO:0055085  transmembrane transport
GO:0019067  viral assembly, maturation, egress, and release
GO:0019058  viral infectious cycle
GO:0019082  viral protein processing
GO:0016032  viral reproduction
GO:0019083  viral transcription
GO:0019068  virion assembly

Cellular Component

GO:0005829  cytosol
GO:0022627  cytosolic small ribosomal subunit
GO:0030666  endocytic vesicle membrane
GO:0010008  endosome membrane
GO:0005654  nucleoplasm
GO:0005886  plasma membrane
GO:0015935  small ribosomal subunit

Molecular Function

GO:0046872  metal ion binding
GO:0003735  structural constituent of ribosome