retinoid X receptor, beta

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Synonym

retinoid X receptor, beta, Retinoic acid receptor RXR-beta, NR2B2, MGC1831, H-2RIIBP, RCoR-1, DAUDI6, RXRB, Retinoid X receptor beta

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:56.90 cerebellum:25.20 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:64.60 artery/aorta:30 vein:- lymphnode:70.80 peripheral blood:109.30 spleen:37.80 thymus:51.50 bone marrow:- adipose:- bone:38.40 skin:38.40
GeneChip cerebrum:7.53 cerebellum:7.82 brain stem:7.38 corpus callosum/glia:7.52 pineal gland:- peripheral nerve:7.51 spine:7.36 retina:- eye:- artery/aorta:7.64 vein:7.58 lymphnode:7.78 peripheral blood:- spleen:7.74 thymus:7.62 bone marrow:7.42 adipose:7.59 bone:- skin:7.46
CAGE cerebrum:3.79 cerebellum:- brain stem:3.74 corpus callosum/glia:3.89 pineal gland:3.40 peripheral nerve:- spine:3.44 retina:- eye:- artery/aorta:3.75 vein:3.71 lymphnode:3.44 peripheral blood:- spleen:3.39 thymus:3.72 bone marrow:- adipose:3.88 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:47.40 prostate:67.60 ovary:74.50 testis:51.90 heart:127.70 muscle:- esophagus:- stomach:42.50 intestine:- colon:25.40     liver/hepato:73.90        lung:14.70    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:62.20 breast:18.60 salivary:-
GeneChip uterus:7.59 placenta:7.55 prostate:7.44 ovary:7.58 testis:7.11 heart:7.16 muscle:7.40 esophagus:7.65 stomach:7.51 intestine:7.20 colon:7.55 liver/hepato:7.56 lung:7.74 bladder:- kidney:7.54 pituitary:7.70 thyroid/parathyroid:7.99 adrenal gland:7.60 pancreas:7.24 breast:7.77 salivary:7.42
CAGE uterus:3.92 placenta:3.87 prostate:3.95 ovary:3.69 testis:3.53 heart:3.49 muscle:3.67 esophagus:3.60 stomach:- intestine:3.32 colon:3.84     liver/hepato:3.55    lung:3.52 bladder:3.65 kidney:3.39 pituitary:3.73 thyroid/parathyroid:4.01 adrenal gland:- pancreas:3.45 breast:3.33 salivary:3.67
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_021976
Gene ID 6257
Unigene ID Hs.388034
Probe set ID 209148_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204231
ENSG00000228333
GTEx ID ENSG00000204231
ENSG00000228333

Orthologous Gene

Mouse[1]  NM_001205214, NM_001205215, NM_001205216, NM_011306
Rat [0]  

Chromosomal Region

6p21.32  [33,161,365  -  33,168,630]
HSCHR6_MHC_COX  [33,082,997  -  33,090,260]
HSCHR6_MHC_QBL  [33,090,190  -  33,097,456]
HSCHR6_MHC_MCF  [33,331,732  -  33,338,994]
HSCHR6_MHC_DBB  [33,139,275  -  33,146,540]
HSCHR6_MHC_MANN  [33,315,284  -  33,322,549]

Gene Family (Interpro ID)

IPR003078  Retinoic acid receptor
IPR000003  Retinoid X receptor
IPR001723  Steroid hormone receptor
IPR003068  Transcription factor COUP
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

1310259
1315958
1331778
1514958
1662118
7481822
7556191
7705655
7758108
7990953
8034312
8125298
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12477932
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14574404
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15207008
15489334
15589691
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15625236
15635645
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17916375
18217139
18375961
18660489
18676680
19170196
19223982
19255064
19453261
19471022
19625176
19692168
19811264
19851445
19888660
19913121
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20211142
20587610
20628086
21693764
21890473
21906983
21923909
21988832
22242598
22322885
23000965
23740775
24183235
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0060038  cardiac muscle cell proliferation
GO:0071300  cellular response to retinoic acid
GO:0010467  gene expression
GO:0001701  in utero embryonic development
GO:0001893  maternal placenta development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0055012  ventricular cardiac muscle cell differentiation

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0044212  DNA regulatory region binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0005515  protein binding
GO:0004886  retinoid-X receptor activity
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding