S100 calcium binding protein A8

Synonym

CFAG, Cystic fibrosis antigen, Calgranulin-A, 60B8AG, Protein S100-A8, Calprotectin L1L subunit, CGLA, S100 calcium binding protein A8, L1Ag, Migration inhibitory factor-related protein 8, MRP-8, MA387, CAGA, CP-10, S100 calcium binding protein A8 (calgranulin A), Urinary stone protein band A, S100A8, S100 calcium-binding protein A8, NIF, S100 calcium-binding protein A8 (calgranulin A), Leukocyte L1 complex light chain, P8

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:23.50

artery/aorta:89.90

vein:-

lymphnode:576.30

peripheral blood:164

spleen:94.50

thymus:-

bone marrow:2322.30

adipose:40.30

bone:38.40

skin:508.80

GeneChip

cerebrum:4.36

cerebellum:3.17

brain stem:4.73

corpus callosum/glia:3.85

pineal gland:-

peripheral nerve:4.21

spine:4.88

retina:-

eye:-

artery/aorta:5.28

vein:6.74

lymphnode:10.11

peripheral blood:-

spleen:10.83

thymus:9.98

bone marrow:13.70

adipose:7.39

bone:-

skin:11.25

CAGE

cerebrum:2.26

cerebellum:-

brain stem:2.74

corpus callosum/glia:1.98

pineal gland:2.21

peripheral nerve:-

spine:3.18

retina:-

eye:-

artery/aorta:2.81

vein:3.24

lymphnode:7.27

peripheral blood:-

spleen:6.34

thymus:3.42

bone marrow:-

adipose:3.25

bone:-

skin:-

RNA-seq

cerebrum:5.82

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:7.94

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:9.96

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:100.20

placenta:29.10

prostate:22.50

ovary:-

testis:17.30

heart:76.60

muscle:281.30

esophagus:685.60

stomach:21.20

intestine:-

colon:8.50

liver/hepato:-

lung:92.90

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:-

pancreas:8.90

breast:-

salivary:-

GeneChip

uterus:6.76

placenta:8.12

prostate:5.17

ovary:5.09

testis:6.16

heart:7.38

muscle:3.93

esophagus:13.99

stomach:6.68

intestine:6.54

colon:8.44

liver/hepato:7.32

lung:10.29

bladder:-

kidney:5.21

pituitary:4.14

thyroid/parathyroid:5.57

adrenal gland:4.71

pancreas:7.78

breast:7.65

salivary:5.45

CAGE

uterus:6.29

placenta:4.01

prostate:2.99

ovary:3.32

testis:2.06

heart:4.09

muscle:3.18

esophagus:8.62

stomach:-

intestine:2.39

colon:2.15

liver/hepato:3.51

lung:5.32

bladder:3.28

kidney:2.80

pituitary:2.78

thyroid/parathyroid:4.07

adrenal gland:-

pancreas:3.32

breast:2.02

salivary:4.77

RNA-seq

uterus:-

placenta:-

prostate:5.90

ovary:4.17

testis:6.08

heart:4.84

muscle:3.64

esophagus:-

stomach:-

intestine:-

colon:5.22

liver/hepato:5.91

lung:10.76

bladder:-

kidney:4.89

pituitary:-

thyroid/parathyroid:4.77

adrenal gland:6.47

pancreas:-

breast:3.65

salivary:-

IDs

Refseq ID	NM_002964
Gene ID	6279
Unigene ID	Hs.416073
Probe set ID	202917_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000143546
GTEx ID	ENSG00000143546

Orthologous Gene

Mouse[1]	NM_013650
Rat[1]	NM_053822

Chromosomal Region

1q21.3 [153,362,508 - 153,363,664]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR018249

EF-HAND 2

Gene Ontology (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0002526	acute inflammatory response
GO:0006914	autophagy
GO:0032602	chemokine production
GO:0002544	chronic inflammatory response
GO:0001816	cytokine production
GO:0042742	defense response to bacterium
GO:0050832	defense response to fungus
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0002523	leukocyte migration during inflammatory response
GO:0070488	neutrophil aggregation
GO:0030593	neutrophil chemotaxis
GO:0030307	positive regulation of cell growth
GO:0050729	positive regulation of inflammatory response
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051493	regulation of cytoskeleton organization
GO:0045471	response to ethanol
GO:0032496	response to lipopolysaccharide
GO:0010043	response to zinc ion
GO:0032119	sequestering of zinc ion
GO:0042060	wound healing

Cellular Component

GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005886	plasma membrane

Molecular Function

GO:0050544	arachidonic acid binding
GO:0005509	calcium ion binding
GO:0008017	microtubule binding
GO:0005515	protein binding
GO:0050786	RAGE receptor binding
GO:0008270	zinc ion binding

S100 calcium binding protein A8

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function