complement factor B

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Synonym

Glycine-rich beta glycoprotein, GBG, Complement factor B precursor, H2-Bf, CFAB, BFD, PBF2, Properdin factor B, C3/C5 convertase, complement factor B, BF, CFB

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.50 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:76.40 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:75.60 thymus:38.70 bone marrow:19.70 adipose:242 bone:358.30 skin:43.20
GeneChip cerebrum:5.20 cerebellum:5.28 brain stem:5.35 corpus callosum/glia:5.23 pineal gland:- peripheral nerve:5.96 spine:5.55 retina:- eye:- artery/aorta:7.49 vein:6.45 lymphnode:6.52 peripheral blood:- spleen:5.90 thymus:5.69 bone marrow:5.11 adipose:7.03 bone:- skin:5.92
CAGE cerebrum:1.05 cerebellum:- brain stem:1.66 corpus callosum/glia:1.59 pineal gland:2.11 peripheral nerve:- spine:1.98 retina:- eye:- artery/aorta:2.95 vein:2.52 lymphnode:2.93 peripheral blood:- spleen:2.23 thymus:1.22 bone marrow:- adipose:2.45 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:83.80 prostate:78.90 ovary:37.30 testis:21.60 heart:51.10 muscle:20.10 esophagus:- stomach:573.50 intestine:194.40 colon:203.50     liver/hepato:1710        lung:180.80    bladder:2261 kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:17.80 breast:195.20 salivary:328.40
GeneChip uterus:5.90 placenta:7.97 prostate:6.84 ovary:7.58 testis:4.77 heart:6.95 muscle:5.21 esophagus:5.95 stomach:7.81 intestine:7.17 colon:6.48 liver/hepato:11.58 lung:7.22 bladder:- kidney:6.12 pituitary:5.44 thyroid/parathyroid:5.67 adrenal gland:5.54 pancreas:6.39 breast:7.40 salivary:5.98
CAGE uterus:2.08 placenta:3.61 prostate:3.28 ovary:3.32 testis:1.98 heart:2.63 muscle:0.78 esophagus:3.11 stomach:- intestine:3.46 colon:2.77     liver/hepato:8.20    lung:3.45 bladder:2.45 kidney:4.98 pituitary:2.42 thyroid/parathyroid:2.74 adrenal gland:- pancreas:3.92 breast:3.24 salivary:2.39
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001710
Gene ID 629
Unigene ID Hs.69771
Probe set ID 202357_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000243649
GTEx ID ENSG00000243649

Orthologous Gene

Mouse[2]  NM_001142706, NM_008198
Rat [0]  

Chromosomal Region

HSCHR6_MHC_QBL  [31,885,871  -  31,910,258]
HSCHR6_MHC_DBB  [31,877,665  -  31,902,052]
HSCHR6_MHC_COX  [31,883,027  -  31,907,413]
HSCHR6_MHC_MANN  [31,952,850  -  31,957,964]
HSCHR6_MHC_SSTO  [31,887,377  -  31,911,713]
HSCHR6_MHC_MCF  [31,971,973  -  31,996,308]
6p21.33  [31,895,475  -  31,919,861]
LRG_136  [5,001  -  11,141]

Gene Family (Interpro ID)

IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like
IPR000436  Sushi/SCR/CCP

Link to Pubmed  (Pubmed ID)

162484
279011
889587
1445220
1545147
2006911
2249879
3052276
3140783
3315100
3643061
6149579
6308626
6323161
6342610
6546754
6957884
8125298
8181962
8225386
8247029
8648130
10072540
10072631
10610782
10637221
10861231
11341920
11367526
11367533
11803045
12477932
14574404
14656967
15174051
15199963
15489334
15582749
15648851
16061287
16301317
16335952
16502470
16518403
17310251
17359931
17395591
17576744
17767156
17916747
17921140
18039777
18096230
18325906
18493315
18502988
18515590
18806293
18806297
18928972
18936151
18987644
19000152
19001225
19005416
19015224
19117936
19143814
19167759
19169232
19187590
19255449
19259132
19277984
19279234
19336475
19344414
19399715
19423540
19556007
19574954
19603351
19661236
19696172
19825847
19833879
19834535
19838195
19851445
19899988
19913121
20007824
20106822
20108004
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20157618
20193965
20205591
20301541
20378180
20385819
20385826
20406964
20438785
20466734
20513133
20523265
20575108
20587610
20628086
20801516
20837143
20848568
20861866
20888482
21163532
21205667
21282580
21541267
21555552
21665990
21816153
21862585
21988832
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22234447
22273503
22542119
22694956
22705344
22714898
22869612
22930722
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23233260
23235567
23263863
23356914
23455636
23535732
23577725
23624872
23750785
23864767
24287422
24557084

Gene Ontology  (GO ID)

Biological Process

GO:0006956  complement activation
GO:0006957  complement activation, alternative pathway
GO:0045087  innate immune response
GO:0006508  proteolysis
GO:0030449  regulation of complement activation

Cellular Component

GO:0005576  extracellular region
GO:0005886  plasma membrane

Molecular Function

GO:0001848  complement binding
GO:0004252  serine-type endopeptidase activity