sal-like 1 (Drosophila)

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Synonym

Zinc finger protein SALL1, ZNF794, sal (Drosophila)-like 1, TBS, HSAL1, Sal-like protein 1, Hsal1, sal-like 1 (Drosophila), HSal1, SAL1, Spalt-like transcription factor 1, SALL1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.80 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:5.24 cerebellum:3.57 brain stem:5.74 corpus callosum/glia:6.88 pineal gland:- peripheral nerve:3.34 spine:7.38 retina:- eye:- artery/aorta:3.12 vein:3.24 lymphnode:3.07 peripheral blood:- spleen:3.04 thymus:3.18 bone marrow:3.21 adipose:3.17 bone:- skin:3.21
CAGE cerebrum:3.07 cerebellum:- brain stem:3.87 corpus callosum/glia:4.45 pineal gland:4.32 peripheral nerve:- spine:3.85 retina:- eye:- artery/aorta:0.34 vein:0.18 lymphnode:0.06 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:2.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.03 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:7.30 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:104 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:6.25 placenta:3.59 prostate:3.41 ovary:4.05 testis:3.38 heart:3.20 muscle:3.28 esophagus:3.06 stomach:3.45 intestine:3.18 colon:3.68 liver/hepato:6.71 lung:3.03 bladder:- kidney:7.07 pituitary:4.38 thyroid/parathyroid:6.85 adrenal gland:3.05 pancreas:3.49 breast:3.18 salivary:3.05
CAGE uterus:3.26 placenta:1.05 prostate:0.85 ovary:1.72 testis:0.75 heart:0.89 muscle:0.25 esophagus:0.26 stomach:- intestine:0.77 colon:0.95     liver/hepato:3.88    lung:0 bladder:1.15 kidney:3.79 pituitary:2.24 thyroid/parathyroid:3.56 adrenal gland:- pancreas:0.58 breast:0.90 salivary:0
RNA-seq uterus:- placenta:- prostate:0.40 ovary:1.72 testis:1.62 heart:0.10 muscle:0 esophagus:- stomach:- intestine:- colon:0.24     liver/hepato:3.53        lung:0    bladder:- kidney:4.45 pituitary:- thyroid/parathyroid:4.14 adrenal gland:0.02 pancreas:- breast:0.17 salivary:-

Gene Information

IDs

Refseq ID NM_002968
Gene ID 6299
Unigene ID Hs.135787
Probe set ID 206893_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000103449
GTEx ID ENSG00000103449

Orthologous Gene

Mouse[1]  NM_021390
Rat[1]  NM_001107415

Chromosomal Region

16q12.1  [51,169,886  -  51,185,181]

Gene Family (Interpro ID)

IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

8975705
9425907
9973281
10533063
10928856
10965108
11484202
11511981
11751684
11836251
12065233
12200128
12395297
12477932
15158448
15342556
16088922
16221172
16344560
16429401
16443351
16545361
16670092
16971658
17426652
17910067
18000979
18024993
18280297
18297069
18470945
19005989
19213029
19247946
19440552
19471022
19942929
20301618
20548946
20634891
21062744
21139048
21300955
21532573
22308078
22504420
23069192
23643386
24165912

Gene Ontology  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0048566  embryonic gut development
GO:0035136  forelimb morphogenesis
GO:0008406  gonad development
GO:0007507  heart development
GO:0035137  hindlimb morphogenesis
GO:0016575  histone deacetylation
GO:0031129  inductive cell-cell signaling
GO:0001822  kidney development
GO:0060173  limb development
GO:0003337  mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0045879  negative regulation of smoothened signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001843  neural tube closure
GO:0021889  olfactory bulb interneuron differentiation
GO:0021553  olfactory nerve development
GO:0042473  outer ear morphogenesis
GO:0021983  pituitary gland development
GO:0045666  positive regulation of neuron differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0006351  transcription, DNA-dependent
GO:0001657  ureteric bud development
GO:0003281  ventricular septum development

Cellular Component

GO:0010369  chromocenter
GO:0005737  cytoplasm
GO:0000792  heterochromatin
GO:0005634  nucleus
GO:0016581  NuRD complex

Molecular Function

GO:0008013  beta-catenin binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0004407  histone deacetylase activity
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0003700  transcription factor activity