spermidine/spermine N1-acetyltransferase 1

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Synonym

KFSD, SSAT-1, Diamine acetyltransferase 1, SSAT, spermidine/spermine N1-acetyltransferase, Spermidine/spermine N(1)-acetyltransferase 1, Polyamine N-acetyltransferase 1, SAT, spermidine/spermine N1-acetyltransferase 1, DC21, Putrescine acetyltransferase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:99.60 cerebellum:50.40 brain stem:- corpus callosum/glia:262.50 pineal gland:148.30 peripheral nerve:490.80 spine:224.60 retina:118.60 eye:282.10 artery/aorta:89.90 vein:- lymphnode:323.50 peripheral blood:400.80 spleen:926.40 thymus:193.30 bone marrow:373.90 adipose:484 bone:115.20 skin:542.40
GeneChip cerebrum:9.10 cerebellum:7.76 brain stem:9.25 corpus callosum/glia:9.24 pineal gland:- peripheral nerve:10.07 spine:10.31 retina:- eye:- artery/aorta:10.73 vein:10.16 lymphnode:10.60 peripheral blood:- spleen:10.85 thymus:10.51 bone marrow:11.15 adipose:10.57 bone:- skin:9.99
CAGE cerebrum:5.71 cerebellum:- brain stem:5.50 corpus callosum/glia:5.39 pineal gland:6.13 peripheral nerve:- spine:6.70 retina:- eye:- artery/aorta:6.35 vein:5.92 lymphnode:6.28 peripheral blood:- spleen:6.81 thymus:5.11 bone marrow:- adipose:5.92 bone:- skin:-
RNA-seq cerebrum:6.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:7.79 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.98 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:273.40 placenta:521 prostate:450.60 ovary:931.60 testis:73.50 heart:204.30 muscle:140.60 esophagus:- stomach:127.50 intestine:615.60 colon:271.30     liver/hepato:496.10        lung:953.10    bladder:1633 kidney:311.90 pituitary:347.90 thyroid/parathyroid:982.50 adrenal gland:457.10 pancreas:160 breast:604 salivary:328.40
GeneChip uterus:10.16 placenta:11.82 prostate:11.12 ovary:10.11 testis:9.52 heart:9.80 muscle:7.34 esophagus:10.15 stomach:10.65 intestine:10.10 colon:9.90 liver/hepato:11.13 lung:11.41 bladder:- kidney:10.95 pituitary:10.44 thyroid/parathyroid:11.49 adrenal gland:10.41 pancreas:9.02 breast:9.71 salivary:10.07
CAGE uterus:5.75 placenta:7.28 prostate:5.74 ovary:5.24 testis:5.62 heart:6.36 muscle:4.60 esophagus:6.18 stomach:- intestine:6.29 colon:5.84     liver/hepato:6.35    lung:7.05 bladder:5.96 kidney:6.36 pituitary:6.66 thyroid/parathyroid:6.48 adrenal gland:- pancreas:5.11 breast:5.94 salivary:5.95
RNA-seq uterus:- placenta:- prostate:7.13 ovary:5.83 testis:6.49 heart:5.70 muscle:4.37 esophagus:- stomach:- intestine:- colon:7.38     liver/hepato:7.40        lung:10.77    bladder:- kidney:7.62 pituitary:- thyroid/parathyroid:8.28 adrenal gland:7.12 pancreas:- breast:7.24 salivary:-

Gene Information

IDs

Refseq ID NM_002970
Gene ID 6303
Unigene ID Hs.28491
Probe set ID 203455_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130066
GTEx ID ENSG00000130066

Orthologous Gene

Mouse[1]  NM_009121
Rat[1]  NM_001007667

Chromosomal Region

Xp22.11  [23,801,290  -  23,804,343]

Gene Family (Interpro ID)

IPR016181  Acyl-CoA N-acyltransferase
IPR000182  GCN5-related N-acetyltransferase

Link to Pubmed  (Pubmed ID)

1417826
1652956
1985966
1989509
2241897
8033120
8573111
8670140
8954982
10646846
11256614
11485561
11779193
11866539
12083816
12215835
12427553
12477932
12539042
12600646
12803540
14506281
15146197
15159132
15213272
15479742
15489334
15905201
16169070
16189514
16207710
16262603
16389195
16544326
16637064
16757480
16769699
16854216
17065202
17516632
17875644
18430370
18660501
18759322
19051286
19060904
19149577
19152344
19162121
19446796
19686286
19727732
19851986
19920120
20212040
20628624
21103663
21139048
21152090
21501848
21890473
21906983
21988832
22179681
22354986
23701549
23768751
23891576
23903781

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0034641  cellular nitrogen compound metabolic process
GO:0006596  polyamine biosynthetic process
GO:0006595  polyamine metabolic process
GO:0009447  putrescine catabolic process
GO:0042127  regulation of cell proliferation

Cellular Component

GO:0005829  cytosol
GO:0005622  intracellular

Molecular Function

GO:0004145  diamine N-acetyltransferase activity
GO:0005515  protein binding
GO:0019809  spermidine binding