chemokine (C-C motif) ligand 4

Synonym

H400, chemokine (C-C motif) ligand 4, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, Small inducible cytokine A4 precursor, G-26, MGC126026, LAG-1, Act-2, ACT2, ACT-2, SCYA4, HC21, MGC126025, T-cell activation protein 2, SIS-gamma, MIP-1-beta, CCL4, MIP1B, G-26 T-lymphocyte-secreted protein, MGC104418, SCYA2, AT744.1, MIP-1-beta(1-69), PAT 744

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:131.40

peripheral blood:346.20

spleen:18.90

thymus:-

bone marrow:59

adipose:-

bone:12.80

skin:14.40

GeneChip

cerebrum:5.22

cerebellum:5.22

brain stem:5.27

corpus callosum/glia:6.31

pineal gland:-

peripheral nerve:5.74

spine:7.25

retina:-

eye:-

artery/aorta:6

vein:5.82

lymphnode:6.56

peripheral blood:-

spleen:8.61

thymus:5.91

bone marrow:6.80

adipose:6.46

bone:-

skin:5.47

CAGE

cerebrum:0.10

cerebellum:-

brain stem:0.39

corpus callosum/glia:0.63

pineal gland:0

peripheral nerve:-

spine:0.73

retina:-

eye:-

artery/aorta:1.52

vein:1.39

lymphnode:0.82

peripheral blood:-

spleen:2.07

thymus:0.46

bone marrow:-

adipose:0.96

bone:-

skin:-

RNA-seq

cerebrum:2.47

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.25

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.05

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:40.10

prostate:11.30

ovary:37.30

testis:8.70

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:8.50

liver/hepato:-

lung:44

bladder:-

kidney:62.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:-

salivary:-

GeneChip

uterus:5.74

placenta:6.44

prostate:6.05

ovary:5.58

testis:5.30

heart:5.51

muscle:5.11

esophagus:5.36

stomach:6.21

intestine:5.63

colon:5.71

liver/hepato:6.62

lung:7.44

bladder:-

kidney:5.38

pituitary:5.29

thyroid/parathyroid:5.73

adrenal gland:5.85

pancreas:5.38

breast:5.65

salivary:5.48

CAGE

uterus:0.71

placenta:0.68

prostate:0.66

ovary:0.76

testis:0.31

heart:0.24

muscle:0.13

esophagus:0.82

stomach:-

intestine:0.53

colon:0.32

liver/hepato:0.36

lung:1.56

bladder:0.98

kidney:0.58

pituitary:0.34

thyroid/parathyroid:0.67

adrenal gland:-

pancreas:0

breast:0

salivary:0.83

RNA-seq

uterus:-

placenta:-

prostate:1.67

ovary:2.02

testis:1.22

heart:0.24

muscle:0.11

esophagus:-

stomach:-

intestine:-

colon:0.27

liver/hepato:1.00

lung:5.11

bladder:-

kidney:0.76

pituitary:-

thyroid/parathyroid:0.95

adrenal gland:3.78

pancreas:-

breast:2.38

salivary:-

IDs

Refseq ID	NM_002984
Gene ID	6351
Unigene ID	Hs.75703
Probe set ID	204103_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000129277
GTEx ID	ENSG00000129277

Orthologous Gene

Mouse[1]	NM_013652
Rat [0]

Chromosomal Region

17q12 [34,431,220 - 34,433,014]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001811

Small chemokine, interleukin-8-like

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0007267	cell-cell signaling
GO:0006928	cellular component movement
GO:0006935	chemotaxis
GO:0007163	establishment or maintenance of cell polarity
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0043922	negative regulation by host of viral transcription
GO:0051928	positive regulation of calcium ion transport
GO:0050850	positive regulation of calcium-mediated signaling
GO:0009636	response to toxin
GO:0009615	response to virus
GO:0007165	signal transduction

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space

Molecular Function

GO:0031726	CCR1 chemokine receptor binding
GO:0031730	CCR5 chemokine receptor binding
GO:0008009	chemokine activity
GO:0005125	cytokine activity
GO:0005515	protein binding

chemokine (C-C motif) ligand 4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function