chemokine (C-C motif) ligand 19

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Synonym

MIP3B, MGC34433, Small inducible cytokine A19 precursor, CKb11, Macrophage inflammatory protein 3 beta, exodus-3, chemokine (C-C motif) ligand 19, SCYA19, CK beta-11, Beta chemokine exodus-3, EBI1-ligand chemokine, MIP-3b, CCL19, MIP-3-beta, ELC

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:479.60 vein:- lymphnode:- peripheral blood:- spleen:56.70 thymus:51.50 bone marrow:- adipose:40.30 bone:- skin:120
GeneChip cerebrum:3.83 cerebellum:3.58 brain stem:3.91 corpus callosum/glia:3.75 pineal gland:- peripheral nerve:3.79 spine:3.78 retina:- eye:- artery/aorta:5.03 vein:5.03 lymphnode:9.38 peripheral blood:- spleen:5.36 thymus:9.16 bone marrow:3.72 adipose:5.97 bone:- skin:5.73
CAGE cerebrum:0.82 cerebellum:- brain stem:2.07 corpus callosum/glia:1.82 pineal gland:1.35 peripheral nerve:- spine:1.54 retina:- eye:- artery/aorta:3.31 vein:5.78 lymphnode:7.04 peripheral blood:- spleen:2.77 thymus:5.87 bone marrow:- adipose:3.18 bone:- skin:-
RNA-seq cerebrum:0.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:8.34 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.42 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:22.50 ovary:- testis:- heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:44    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:- salivary:-
GeneChip uterus:4.28 placenta:3.17 prostate:4.71 ovary:4.05 testis:3.47 heart:4.64 muscle:3.82 esophagus:4.48 stomach:5.46 intestine:4.31 colon:6.63 liver/hepato:4.76 lung:4.97 bladder:- kidney:3.70 pituitary:3.87 thyroid/parathyroid:5.16 adrenal gland:3.72 pancreas:4.29 breast:5.19 salivary:4.61
CAGE uterus:2.17 placenta:0 prostate:3.06 ovary:2.83 testis:1.75 heart:3.29 muscle:0.34 esophagus:3.85 stomach:- intestine:1.58 colon:3.13     liver/hepato:2.50    lung:3.72 bladder:2.60 kidney:4.13 pituitary:0.62 thyroid/parathyroid:4.15 adrenal gland:- pancreas:2.08 breast:3.02 salivary:3.74
RNA-seq uterus:- placenta:- prostate:2.58 ovary:1.97 testis:0.98 heart:1.65 muscle:0 esophagus:- stomach:- intestine:- colon:1.23     liver/hepato:1.41        lung:4.28    bladder:- kidney:3.43 pituitary:- thyroid/parathyroid:1.19 adrenal gland:8.00 pancreas:- breast:2.91 salivary:-

Gene Information

IDs

Refseq ID NM_006274
Gene ID 6363
Unigene ID Hs.50002
Probe set ID 210072_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000172724
GTEx ID ENSG00000172724

Orthologous Gene

Mouse[3]  NM_011888
Rat [0]  

Chromosomal Region

9p13.3  [34,689,564  -  34,691,274]

Gene Family (Interpro ID)

IPR001811  Small chemokine, interleukin-8-like

Link to Pubmed  (Pubmed ID)

9013939
9153236
9235955
9498785
9743376
10706668
10861057
11869682
11870628
11929789
11981810
11994492
12474232
12477932
12729902
14592837
14871974
15019823
15059845
15489334
15546958
15674360
15714581
15778365
16081805
16249377
16500130
16678487
16887149
16904643
17082584
17182562
17469160
17597826
17703412
17709502
17825430
17881634
18047937
18240029
18310327
18577758
18757429
18838169
19258923
19540558
19655301
20002784
20015995
20237496
20503287
20592280
20865789
20942936
20969772
21139048
21464944
22288592
22334704
22976543
23071112
23644527
23740460
23898208
23922113
24111618

Gene Ontology  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0007154  cell communication
GO:0048469  cell maturation
GO:0006874  cellular calcium ion homeostasis
GO:0002407  dendritic cell chemotaxis
GO:0001768  establishment of T cell polarity
GO:0001771  formation of immunological synapse
GO:0006955  immune response
GO:0006954  inflammatory response
GO:0002408  myeloid dendritic cell chemotaxis
GO:0043089  positive regulation of Cdc42 GTPase activity
GO:0050921  positive regulation of chemotaxis
GO:0002606  positive regulation of dendritic cell antigen processing and presentation
GO:0045807  positive regulation of endocytosis
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0010560  positive regulation of glycoprotein biosynthetic process
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0032735  positive regulation of interleukin-12 production
GO:0046330  positive regulation of JNK cascade
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0045860  positive regulation of protein kinase activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0032320  positive regulation of Ras GTPase activity
GO:0048260  positive regulation of receptor-mediated endocytosis
GO:0042102  positive regulation of T cell proliferation
GO:0045627  positive regulation of T-helper 1 cell differentiation
GO:0032760  positive regulation of tumor necrosis factor production
GO:0060491  regulation of cell projection assembly
GO:0051209  release of sequestered calcium ion into cytosol
GO:0014070  response to organic cyclic substance
GO:0034695  response to prostaglandin E stimulus
GO:0009615  response to virus
GO:0031295  T cell costimulation

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0048020  CCR chemokine receptor binding
GO:0031735  CCR10 chemokine receptor binding
GO:0031732  CCR7 chemokine receptor binding
GO:0008009  chemokine activity