chemokine (C-X3-C motif) ligand 1

Synonym

Fractalkine precursor, FKN, NTN, A-152E5.2, CX3C membrane-anchored chemokine, CXC3C, fractalkine, chemokine (C-X3-C motif) ligand 1, NTT, ABCD-3, CX3CL1, neurotactin, C3Xkine, SCYD1, CXC3, Neurotactin, Small inducible cytokine D1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:137.50

cerebellum:-

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:122.70

spine:112.30

retina:-

eye:82.30

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:80.70

bone:25.60

skin:9.60

GeneChip

cerebrum:7.18

cerebellum:5.52

brain stem:6.31

corpus callosum/glia:5.71

pineal gland:-

peripheral nerve:5.94

spine:6.67

retina:-

eye:-

artery/aorta:7.30

vein:7.18

lymphnode:5.67

peripheral blood:-

spleen:4.61

thymus:4.78

bone marrow:4.58

adipose:6.86

bone:-

skin:6.22

CAGE

cerebrum:3.86

cerebellum:-

brain stem:3.26

corpus callosum/glia:3.34

pineal gland:4.10

peripheral nerve:-

spine:3.22

retina:-

eye:-

artery/aorta:4.76

vein:3.53

lymphnode:2.29

peripheral blood:-

spleen:0.51

thymus:1.68

bone marrow:-

adipose:4.07

bone:-

skin:-

RNA-seq

cerebrum:3.96

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.94

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.40

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:21.90

prostate:56.30

ovary:-

testis:17.30

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:52.80

lung:58.70

bladder:125.60

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:62.20

breast:74.30

salivary:-

GeneChip

uterus:5.86

placenta:4.89

prostate:6.78

ovary:5.18

testis:5.12

heart:6.24

muscle:5.16

esophagus:5.76

stomach:5.89

intestine:5.86

colon:5.86

liver/hepato:5.77

lung:7.83

bladder:-

kidney:6.93

pituitary:5.25

thyroid/parathyroid:6.17

adrenal gland:5.36

pancreas:5.22

breast:7.83

salivary:6.91

CAGE

uterus:3.69

placenta:1.84

prostate:4.24

ovary:3.08

testis:2.92

heart:3.61

muscle:3.18

esophagus:3.37

stomach:-

intestine:2.37

colon:2.68

liver/hepato:2.37

lung:4.56

bladder:4.30

kidney:3.66

pituitary:2.34

thyroid/parathyroid:2.83

adrenal gland:-

pancreas:2.48

breast:4.49

salivary:4.09

RNA-seq

uterus:-

placenta:-

prostate:5.29

ovary:2.73

testis:4.03

heart:2.70

muscle:3.52

esophagus:-

stomach:-

intestine:-

colon:2.55

liver/hepato:1.28

lung:7.45

bladder:-

kidney:3.46

pituitary:-

thyroid/parathyroid:2.58

adrenal gland:3.37

pancreas:-

breast:4.63

salivary:-

IDs

Refseq ID	NM_002996
Gene ID	6376
Unigene ID	Hs.531668
Probe set ID	823_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000006210
GTEx ID	ENSG00000006210

Orthologous Gene

Mouse[2]	NM_009142
Rat [0]

Chromosomal Region

16q21 [57,406,375 - 57,418,960]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008097	Fractalkine/neurotactin
IPR001811	Small chemokine, interleukin-8-like

Gene Ontology (GO ID)

Biological Process

GO:0060055	angiogenesis involved in wound healing
GO:0007155	cell adhesion
GO:0006935	chemotaxis
GO:0019221	cytokine-mediated signaling pathway
GO:0006952	defense response
GO:0006955	immune response
GO:0050902	leukocyte adhesive activation
GO:0030595	leukocyte chemotaxis
GO:0048247	lymphocyte chemotaxis
GO:0048246	macrophage chemotaxis
GO:0043066	negative regulation of apoptosis
GO:0030593	neutrophil chemotaxis
GO:0045766	positive regulation of angiogenesis
GO:0051041	positive regulation of calcium-independent cell-cell adhesion
GO:0050729	positive regulation of inflammatory response
GO:0032914	positive regulation of transforming growth factor-beta1 production

Cellular Component

GO:0009986	cell surface
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0016021	integral to membrane
GO:0005886	plasma membrane

Molecular Function

GO:0008009	chemokine activity
GO:0005515	protein binding
GO:0005102	receptor binding

chemokine (C-X3-C motif) ligand 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function