dual specificity phosphatase 21

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Synonym

dual specificity phosphatase 21, DUSP21, MGC149878, LMWDSP21, Dual specificity protein phosphatase 21

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.02 cerebellum:4.09 brain stem:4.02 corpus callosum/glia:3.83 pineal gland:- peripheral nerve:3.90 spine:3.93 retina:- eye:- artery/aorta:4.09 vein:4.31 lymphnode:3.94 peripheral blood:- spleen:3.83 thymus:3.89 bone marrow:4.33 adipose:4.06 bone:- skin:4.20
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:21.60 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.84 placenta:3.65 prostate:3.74 ovary:3.87 testis:5.78 heart:4.10 muscle:4.07 esophagus:3.95 stomach:3.84 intestine:4.15 colon:4.08 liver/hepato:4.04 lung:3.79 bladder:- kidney:4.01 pituitary:4.04 thyroid/parathyroid:3.96 adrenal gland:4 pancreas:4.75 breast:3.84 salivary:4.17
CAGE uterus:0 placenta:0.08 prostate:0 ovary:0 testis:1.55 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:2.15 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_022076
Gene ID 63904
Unigene ID Hs.534478
Probe set ID 220515_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000189037
GTEx ID ENSG00000189037

Orthologous Gene

Mouse[1]  NM_028568
Rat [0]  

Chromosomal Region

Xp11.3  [44,703,249  -  44,704,130]

Gene Family (Interpro ID)

IPR020417  Dual specificity phosphatase
IPR000340  Dual specificity phosphatase, catalytic domain
IPR020420  Dual specificity phosphatase, subfamily B
IPR020422  Dual specificity phosphatase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

12408986
12477932
15489334
15772651
21832049
21900206
23929653

Gene Ontology  (GO ID)

Cellular Component

GO:0005737  cytoplasm
GO:0005743  mitochondrial inner membrane
GO:0005634  nucleus

Molecular Function

GO:0017017  MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0004725  protein tyrosine phosphatase activity
GO:0008138  protein tyrosine/serine/threonine phosphatase activity