caspase recruitment domain family, member 9

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Synonym

hCARD9, caspase recruitment domain family, member 9, Caspase recruitment domain-containing protein 9, CARD9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:4.35 cerebellum:4.45 brain stem:4.42 corpus callosum/glia:4.44 pineal gland:- peripheral nerve:4.27 spine:4.43 retina:- eye:- artery/aorta:4.23 vein:4.24 lymphnode:4.68 peripheral blood:- spleen:4.44 thymus:4.23 bone marrow:5.10 adipose:4.38 bone:- skin:4.39
CAGE cerebrum:0.84 cerebellum:- brain stem:1.38 corpus callosum/glia:1.56 pineal gland:0.61 peripheral nerve:- spine:1.42 retina:- eye:- artery/aorta:0.95 vein:1.29 lymphnode:1.54 peripheral blood:- spleen:1.77 thymus:0.54 bone marrow:- adipose:0.71 bone:- skin:-
RNA-seq cerebrum:0.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.57 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.18 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.32 placenta:3.66 prostate:4.04 ovary:4.26 testis:4.13 heart:4.16 muscle:4.24 esophagus:4.23 stomach:4.10 intestine:4.33 colon:4.25 liver/hepato:4.19 lung:4.75 bladder:- kidney:4.21 pituitary:4.27 thyroid/parathyroid:3.91 adrenal gland:4.28 pancreas:4.65 breast:4.43 salivary:4.38
CAGE uterus:0.50 placenta:0.88 prostate:0.88 ovary:0.76 testis:0.16 heart:0.53 muscle:0.05 esophagus:0.46 stomach:- intestine:1.02 colon:0.95     liver/hepato:0.90    lung:1.09 bladder:0.46 kidney:0.58 pituitary:0.50 thyroid/parathyroid:0.32 adrenal gland:- pancreas:0 breast:0.90 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0.30 ovary:0.64 testis:0.37 heart:0.14 muscle:0 esophagus:- stomach:- intestine:- colon:0.04     liver/hepato:0.12        lung:0.06    bladder:- kidney:0.51 pituitary:- thyroid/parathyroid:0.10 adrenal gland:0.95 pancreas:- breast:0.68 salivary:-

Gene Information

IDs

Refseq ID NM_052813
Gene ID 64170
Unigene ID -
Probe set ID 220162_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000187796
GTEx ID ENSG00000187796

Orthologous Gene

Mouse[1]  NM_001037747
Rat[1]  NM_022303

Chromosomal Region

9q34.3  [139,256,355  -  139,268,133]
LRG_178  [5,001  -  14,726]

Gene Family (Interpro ID)

IPR001315  Caspase Recruitment
IPR011029  DEATH-like

Link to Pubmed  (Pubmed ID)

11053425
11259443
12477932
14702039
15164053
15489334
16189514
17187069
17936701
18439550
19809088
19864672
19915572
20228799
20237496
20463747
21102463
21297633
21425313
21436691
21743469
21881131
21985303
22013052
22423967
22936669
23017229
23128233
23251661
24018495
24068945
24131138
24231284

Gene Ontology  (GO ID)

Biological Process

GO:0050830  defense response to Gram-positive bacterium
GO:0051607  defense response to virus
GO:0045087  innate immune response
GO:0070423  nucleotide-binding oligomerization domain containing signaling pathway
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0032874  positive regulation of stress-activated MAPK cascade
GO:0032760  positive regulation of tumor necrosis factor production
GO:0042981  regulation of apoptosis
GO:0045076  regulation of interleukin-2 biosynthetic process
GO:0045408  regulation of interleukin-6 biosynthetic process
GO:0042534  regulation of tumor necrosis factor biosynthetic process
GO:0042493  response to drug
GO:0043330  response to exogenous dsRNA
GO:0009620  response to fungus
GO:0032495  response to muramyl dipeptide
GO:0032494  response to peptidoglycan

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0050700  CARD domain binding
GO:0042803  protein homodimerization activity