secreted frizzled-related protein 1

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FRP1, FrzA, FRP-1, Secreted frizzled-related protein 1 precursor, Frizzled-related protein 1, SARP-2, secreted frizzled-related protein 1, SFRP1, sFRP-1, SARP2, Secreted apoptosis-related protein 2

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.90 cerebellum:4.67 brain stem:3.95 corpus callosum/glia:4.67 pineal gland:- peripheral nerve:4.69 spine:3.37 retina:- eye:- artery/aorta:5.92 vein:5.16 lymphnode:3.87 peripheral blood:- spleen:4.69 thymus:3.14 bone marrow:3.19 adipose:5.43 bone:- skin:4.98
CAGE cerebrum:2.81 cerebellum:- brain stem:3.16 corpus callosum/glia:4.12 pineal gland:0.79 peripheral nerve:- spine:2.31 retina:- eye:- artery/aorta:4.73 vein:3.77 lymphnode:2.08 peripheral blood:- spleen:2.86 thymus:0.50 bone marrow:- adipose:3.49 bone:- skin:-
RNA-seq cerebrum:3.44 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.49 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.82 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.57 placenta:3.44 prostate:5.32 ovary:5.66 testis:5.15 heart:6.44 muscle:3.44 esophagus:5.35 stomach:5.62 intestine:4.33 colon:4.46 liver/hepato:3.46 lung:3.33 bladder:- kidney:6.55 pituitary:3.21 thyroid/parathyroid:4.33 adrenal gland:4.47 pancreas:4.05 breast:7.61 salivary:7.79
CAGE uterus:5.14 placenta:3.64 prostate:4.00 ovary:3.92 testis:4.01 heart:4.18 muscle:1.13 esophagus:3.64 stomach:- intestine:2.94 colon:3.32     liver/hepato:1.44    lung:1.82 bladder:3.71 kidney:4.71 pituitary:1.03 thyroid/parathyroid:2.32 adrenal gland:- pancreas:1.21 breast:4.75 salivary:5.32
RNA-seq uterus:- placenta:- prostate:5.00 ovary:5.02 testis:5.83 heart:3.67 muscle:1.43 esophagus:- stomach:- intestine:- colon:5.01     liver/hepato:1.04        lung:2.37    bladder:- kidney:6.16 pituitary:- thyroid/parathyroid:2.95 adrenal gland:3.20 pancreas:- breast:6.67 salivary:-


Refseq ID NM_003012
Gene ID 6422
Unigene ID -
Probe set ID 202035_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000104332
GTEx ID ENSG00000104332

Orthologous Gene

Mouse[3]  NM_013834
Rat[3]  NM_013834

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0060346  bone trabecula formation
GO:0007420  brain development
GO:0071392  cellular response to estradiol stimulus
GO:0071391  cellular response to estrogen stimulus
GO:0071363  cellular response to growth factor stimulus
GO:0071504  cellular response to heparin
GO:0071456  cellular response to hypoxia
GO:0071347  cellular response to interleukin-1
GO:0071380  cellular response to prostaglandin E stimulus
GO:0009267  cellular response to starvation
GO:0071356  cellular response to tumor necrosis factor
GO:0071305  cellular response to vitamin D
GO:0071481  cellular response to X-ray
GO:0048546  digestive tract morphogenesis
GO:0006309  DNA fragmentation involved in apoptosis
GO:0009950  dorsal/ventral axis specification
GO:0009790  embryonic development
GO:0008585  female gonad development
GO:0008406  gonad development
GO:0002244  hemopoietic progenitor cell differentiation
GO:0060218  hemopoietic stem cell differentiation
GO:0008584  male gonad development
GO:0022601  menstrual cycle phase
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0045578  negative regulation of B cell differentiation
GO:0030514  negative regulation of BMP signaling pathway
GO:0046851  negative regulation of bone remodeling
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0048147  negative regulation of fibroblast proliferation
GO:0010629  negative regulation of gene expression
GO:0046676  negative regulation of insulin secretion
GO:0043508  negative regulation of JUN kinase activity
GO:0030279  negative regulation of ossification
GO:0045668  negative regulation of osteoblast differentiation
GO:0033689  negative regulation of osteoblast proliferation
GO:0045671  negative regulation of osteoclast differentiation
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0014034  neural crest cell fate commitment
GO:0001843  neural tube closure
GO:0001649  osteoblast differentiation
GO:0090179  planar cell polarity pathway involved in neural tube closure
GO:0043065  positive regulation of apoptosis
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045600  positive regulation of fat cell differentiation
GO:0051894  positive regulation of focal adhesion formation
GO:0032855  positive regulation of Rac GTPase activity
GO:0045880  positive regulation of smoothened signaling pathway
GO:0051496  positive regulation of stress fiber formation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0060527  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0045765  regulation of angiogenesis
GO:0060687  regulation of branching involved in prostate gland morphogenesis
GO:0010564  regulation of cell cycle process
GO:0042493  response to drug
GO:0014070  response to organic cyclic substance
GO:0035019  somatic stem cell maintenance
GO:0001657  ureteric bud development
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0042995  cell projection
GO:0009986  cell surface
GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005615  extracellular space
GO:0005622  intracellular
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0008144  drug binding
GO:0005109  frizzled binding
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0030165  PDZ domain binding
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding