RAB17, member RAS oncogene family

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Synonym

FLJ12538, RAB17, member RAS oncogene family, Ras-related protein Rab-17, RAB17

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.93 cerebellum:6.16 brain stem:5.86 corpus callosum/glia:5.80 pineal gland:- peripheral nerve:5.51 spine:5.57 retina:- eye:- artery/aorta:6.34 vein:6.15 lymphnode:5.66 peripheral blood:- spleen:5.60 thymus:5.44 bone marrow:5.88 adipose:5.95 bone:- skin:6.10
CAGE cerebrum:0.14 cerebellum:- brain stem:0.13 corpus callosum/glia:0.76 pineal gland:0.14 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.79 vein:0.18 lymphnode:0.37 peripheral blood:- spleen:0 thymus:0.28 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.11 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6 placenta:6.84 prostate:6.29 ovary:6.27 testis:5.61 heart:6.15 muscle:6.27 esophagus:6.31 stomach:7.14 intestine:7.05 colon:6.64 liver/hepato:8.60 lung:7.23 bladder:- kidney:8.89 pituitary:6.65 thyroid/parathyroid:7.61 adrenal gland:5.82 pancreas:6.52 breast:6.65 salivary:8.44
CAGE uterus:0.60 placenta:2.18 prostate:1.19 ovary:0.42 testis:0.34 heart:0 muscle:0 esophagus:0.73 stomach:- intestine:4.27 colon:3.05     liver/hepato:3.69    lung:2.56 bladder:0.58 kidney:3.31 pituitary:1.28 thyroid/parathyroid:3.39 adrenal gland:- pancreas:3.32 breast:1.53 salivary:3.21
RNA-seq uterus:- placenta:- prostate:1.62 ovary:0.58 testis:0.71 heart:0.54 muscle:0 esophagus:- stomach:- intestine:- colon:0.23     liver/hepato:4.63        lung:2.29    bladder:- kidney:4.32 pituitary:- thyroid/parathyroid:3.53 adrenal gland:0.40 pancreas:- breast:0.51 salivary:-

Gene Information

IDs

Refseq ID NM_022449
Gene ID 64284
Unigene ID -
Probe set ID 218931_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000124839
GTEx ID ENSG00000124839

Orthologous Gene

Mouse[4]  NM_001159725, NM_008998
Rat[1]  NM_001109363, NM_008998

Chromosomal Region

2q37.3  [238,482,965  -  238,510,257]

Gene Family (Interpro ID)

IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

8125298
8486736
9624171
10329441
11076863
11230166
11256614
12477932
14702039
15342556
15489334
15489336
15761153
16169070
16381901
17353931
19056867
20379614
21291502
22328529
23251661

Gene Ontology  (GO ID)

Biological Process

GO:0032456  endocytic recycling
GO:0032401  establishment of melanosome localization
GO:0046847  filopodium assembly
GO:0002415  immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
GO:0032402  melanosome transport
GO:0015031  protein transport
GO:0050773  regulation of dendrite development
GO:0051489  regulation of filopodium assembly
GO:0051963  regulation of synaptogenesis
GO:0007264  small GTPase mediated signal transduction
GO:0045056  transcytosis

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0043025  cell soma
GO:0030425  dendrite
GO:0005622  intracellular
GO:0042470  melanosome
GO:0055037  recycling endosome
GO:0055038  recycling endosome membrane

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding