nucleoredoxin

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Synonym

TRG-4, nucleoredoxin, NXN, FLJ12614

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:16.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:445 peripheral nerve:61.30 spine:- retina:237.30 eye:58.80 artery/aorta:- vein:66.60 lymphnode:10.10 peripheral blood:- spleen:- thymus:38.70 bone marrow:19.70 adipose:80.70 bone:- skin:129.60
GeneChip cerebrum:6.12 cerebellum:5.58 brain stem:6.20 corpus callosum/glia:6.03 pineal gland:- peripheral nerve:6.36 spine:6.17 retina:- eye:- artery/aorta:7.86 vein:7.78 lymphnode:7.29 peripheral blood:- spleen:6.27 thymus:6.83 bone marrow:5.37 adipose:7.08 bone:- skin:7.49
CAGE cerebrum:2.18 cerebellum:- brain stem:2.32 corpus callosum/glia:2.43 pineal gland:2.90 peripheral nerve:- spine:2.48 retina:- eye:- artery/aorta:3.46 vein:3.06 lymphnode:3.07 peripheral blood:- spleen:1.65 thymus:2.42 bone marrow:- adipose:3.26 bone:- skin:-
RNA-seq cerebrum:0.46 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.98 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.39 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:54.60 prostate:157.70 ovary:111.80 testis:34.60 heart:102.20 muscle:80.40 esophagus:- stomach:106.20 intestine:32.40 colon:161.10     liver/hepato:42.20        lung:88    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:65.10 salivary:-
GeneChip uterus:8.46 placenta:6.14 prostate:8.37 ovary:7.57 testis:6.94 heart:6.92 muscle:8.43 esophagus:7.82 stomach:7.58 intestine:7.74 colon:7.54 liver/hepato:6.08 lung:8.24 bladder:- kidney:6.32 pituitary:6.07 thyroid/parathyroid:7.10 adrenal gland:6.67 pancreas:7.34 breast:7.75 salivary:7.41
CAGE uterus:3.95 placenta:2.51 prostate:3.77 ovary:3.41 testis:2.85 heart:3.06 muscle:4.21 esophagus:3.40 stomach:- intestine:2.71 colon:3.52     liver/hepato:2.01    lung:3.68 bladder:3.78 kidney:2.02 pituitary:1.83 thyroid/parathyroid:2.44 adrenal gland:- pancreas:3.84 breast:3.45 salivary:3.19
RNA-seq uterus:- placenta:- prostate:3.24 ovary:2.05 testis:1.61 heart:1.33 muscle:4.43 esophagus:- stomach:- intestine:- colon:2.69     liver/hepato:1.19        lung:3.00    bladder:- kidney:0.67 pituitary:- thyroid/parathyroid:2.02 adrenal gland:2.20 pancreas:- breast:1.22 salivary:-

Gene Information

IDs

Refseq ID NM_022463
Gene ID 64359
Unigene ID Hs.527989
Probe set ID 219489_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000167693
GTEx ID ENSG00000167693

Orthologous Gene

Mouse[2]  NM_008750
Rat[2]  NM_008750

Chromosomal Region

17p13.3  [702,581  -  883,010]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9119370
10737800
10903915
12477932
14702039
16764867
17353931
17567240
19308021
19322201
19615732
21139048
21251912
21890473
21906983
22566634
23000965
23300278
23535732

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0031397  negative regulation of protein ubiquitination
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0047134  protein-disulfide reductase activity
GO:0004791  thioredoxin-disulfide reductase activity