gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)

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Synonym

Gremlin-2 precursor, DAND3, Cysteine knot superfamily 1, BMP antagonist 2, CKTSF1B2, Protein related to DAN and cerberus, FLJ21195, Prdc, GREM2, PRDC

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.50 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:64 skin:4.80
GeneChip cerebrum:4.78 cerebellum:3.83 brain stem:4.37 corpus callosum/glia:3.64 pineal gland:- peripheral nerve:4.69 spine:4.17 retina:- eye:- artery/aorta:4.05 vein:6.30 lymphnode:3.98 peripheral blood:- spleen:3.80 thymus:3.42 bone marrow:3.85 adipose:3.61 bone:- skin:4.46
CAGE cerebrum:1.83 cerebellum:- brain stem:1.12 corpus callosum/glia:0.94 pineal gland:3.04 peripheral nerve:- spine:1.67 retina:- eye:- artery/aorta:1.79 vein:1.80 lymphnode:1.62 peripheral blood:- spleen:0.99 thymus:0 bone marrow:- adipose:0.46 bone:- skin:-
RNA-seq cerebrum:1.99 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.38 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:22.50 ovary:37.30 testis:13 heart:38.30 muscle:- esophagus:- stomach:- intestine:97.20 colon:50.90     liver/hepato:147.80        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.68 placenta:5.32 prostate:4.49 ovary:4.08 testis:3.43 heart:4.19 muscle:4.23 esophagus:5.67 stomach:5.98 intestine:5.58 colon:6.14 liver/hepato:7.20 lung:4.18 bladder:- kidney:3.70 pituitary:4.49 thyroid/parathyroid:3.62 adrenal gland:4.52 pancreas:3.80 breast:4.59 salivary:5.31
CAGE uterus:2.19 placenta:2.54 prostate:1.87 ovary:1.67 testis:0.68 heart:0.85 muscle:1.63 esophagus:2.19 stomach:- intestine:3.33 colon:3.38     liver/hepato:3.74    lung:1.38 bladder:1.96 kidney:0.49 pituitary:2.73 thyroid/parathyroid:0.28 adrenal gland:- pancreas:0 breast:0.55 salivary:2.83
RNA-seq uterus:- placenta:- prostate:1.21 ovary:0.85 testis:1.85 heart:0.01 muscle:0 esophagus:- stomach:- intestine:- colon:3.41     liver/hepato:2.82        lung:1.06    bladder:- kidney:0.47 pituitary:- thyroid/parathyroid:0.52 adrenal gland:0.86 pancreas:- breast:0.79 salivary:-

Gene Information

IDs

Refseq ID NM_022469
Gene ID 64388
Unigene ID Hs.98206
Probe set ID 220794_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000180875
GTEx ID ENSG00000180875

Orthologous Gene

Mouse[1]  NM_011825
Rat[1]  NM_001105974

Chromosomal Region

1q43  [240,652,873  -  240,775,449]

Gene Family (Interpro ID)

IPR006207  Cystine knot, C-terminal

Link to Pubmed  (Pubmed ID)

12477932
14525956
14702039
15039429
15254711
15489334
15621726
16710414
17029022
19626040
20379614
22199011
22542470
23223679
23437003
23902946

Gene Ontology  (GO ID)

Biological Process

GO:0030509  BMP signaling pathway

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity