AKT interacting protein

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Synonym

fused toes homolog (mouse), Fused toes protein homolog, Ft1, FTS, FT1, FLJ13258, fused toes (mouse) homolog

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:87.70 cerebellum:75.60 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:61.30 spine:112.30 retina:- eye:117.50 artery/aorta:30 vein:66.60 lymphnode:10.10 peripheral blood:54.70 spleen:- thymus:90.20 bone marrow:19.70 adipose:40.30 bone:25.60 skin:43.20
GeneChip cerebrum:8.49 cerebellum:8.12 brain stem:8.87 corpus callosum/glia:8.44 pineal gland:- peripheral nerve:8.11 spine:8.69 retina:- eye:- artery/aorta:7.54 vein:7.80 lymphnode:7.17 peripheral blood:- spleen:6.97 thymus:6.95 bone marrow:6.34 adipose:7.46 bone:- skin:7.44
CAGE cerebrum:2.36 cerebellum:- brain stem:2.99 corpus callosum/glia:2.46 pineal gland:1.73 peripheral nerve:- spine:2.41 retina:- eye:- artery/aorta:2.05 vein:2.20 lymphnode:2.32 peripheral blood:- spleen:2.21 thymus:2.08 bone marrow:- adipose:2.65 bone:- skin:-
RNA-seq cerebrum:0.95 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.66 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:87.40 prostate:45.10 ovary:37.30 testis:56.20 heart:51.10 muscle:80.40 esophagus:- stomach:42.50 intestine:32.40 colon:17     liver/hepato:21.10        lung:34.20    bladder:125.60 kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:62.20 breast:18.60 salivary:-
GeneChip uterus:7.47 placenta:8.64 prostate:7.68 ovary:7.44 testis:7.89 heart:7.79 muscle:8.85 esophagus:7.67 stomach:7.19 intestine:7.23 colon:6.78 liver/hepato:7.17 lung:7.28 bladder:- kidney:7.68 pituitary:8.02 thyroid/parathyroid:7.68 adrenal gland:6.99 pancreas:6.29 breast:7.43 salivary:6.73
CAGE uterus:2.37 placenta:4.02 prostate:2.40 ovary:2.33 testis:2.42 heart:2.46 muscle:2.15 esophagus:2.53 stomach:- intestine:2.67 colon:2.10     liver/hepato:2.61    lung:2.47 bladder:2.54 kidney:2.59 pituitary:1.93 thyroid/parathyroid:2.29 adrenal gland:- pancreas:1.21 breast:2.53 salivary:1.58
RNA-seq uterus:- placenta:- prostate:0.65 ovary:0.96 testis:1.30 heart:0.62 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.66     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.42 pituitary:- thyroid/parathyroid:0.16 adrenal gland:0.15 pancreas:- breast:1.10 salivary:-

Gene Information

IDs

Refseq ID NM_001012398
Gene ID 64400
Unigene ID Hs.380897
Probe set ID 218373_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166971
GTEx ID ENSG00000166971

Orthologous Gene

Mouse[2]  NM_010241
Rat [0]  

Chromosomal Region

16q12.2  [53,524,952  -  53,537,170]

Gene Family (Interpro ID)

IPR000608  Ubiquitin-conjugating enzyme, E2
IPR016135  Ubiquitin-conjugating enzyme/RWD-like

Link to Pubmed  (Pubmed ID)

8125298
8626685
9383278
9501314
12477932
14702039
14749367
15489334
16169070
16189514
17207965
17353931
18029348
18799622
19270026
19549727
20132317
20635389
20945372
21424602
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0045022  early endosome to late endosome transport
GO:0007032  endosome organization
GO:0008333  endosome to lysosome transport
GO:0007040  lysosome organization
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0032092  positive regulation of protein binding
GO:0015031  protein transport

Cellular Component

GO:0005737  cytoplasm
GO:0070695  FHF complex
GO:0005794  Golgi apparatus
GO:0030897  HOPS complex
GO:0005730  nucleolus
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding
GO:0019787  small conjugating protein ligase activity