DEP domain containing 6

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Synonym

DEP domain containing 6, DKFZp564B1778, DEPDC6, FLJ13854, FLJ12428, DEP.6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:34.40 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:112.30 retina:- eye:23.50 artery/aorta:- vein:- lymphnode:- peripheral blood:18.20 spleen:37.80 thymus:- bone marrow:- adipose:322.70 bone:38.40 skin:48
GeneChip cerebrum:6.62 cerebellum:5.38 brain stem:6.84 corpus callosum/glia:7.37 pineal gland:- peripheral nerve:6.66 spine:6.96 retina:- eye:- artery/aorta:5.80 vein:6.67 lymphnode:6.26 peripheral blood:- spleen:6.12 thymus:5.70 bone marrow:5.26 adipose:6.54 bone:- skin:6.12
CAGE cerebrum:3.54 cerebellum:- brain stem:3.82 corpus callosum/glia:4.50 pineal gland:2.63 peripheral nerve:- spine:3.87 retina:- eye:- artery/aorta:3.17 vein:3.22 lymphnode:3.32 peripheral blood:- spleen:3.19 thymus:1.94 bone marrow:- adipose:3.45 bone:- skin:-
RNA-seq cerebrum:2.57 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.44 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.20 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:18.20 prostate:56.30 ovary:- testis:8.70 heart:12.80 muscle:100.50 esophagus:- stomach:127.50 intestine:97.20 colon:17     liver/hepato:-        lung:44    bladder:- kidney:145.60 pituitary:- thyroid/parathyroid:655 adrenal gland:304.70 pancreas:71.10 breast:74.30 salivary:328.40
GeneChip uterus:7.12 placenta:6.20 prostate:7.48 ovary:8.19 testis:5.32 heart:6.26 muscle:9.57 esophagus:6.82 stomach:8.19 intestine:7.62 colon:6.75 liver/hepato:6.67 lung:5.61 bladder:- kidney:8.01 pituitary:6.79 thyroid/parathyroid:9.23 adrenal gland:8.72 pancreas:6.17 breast:7.24 salivary:10.15
CAGE uterus:4.09 placenta:3.15 prostate:3.61 ovary:4.16 testis:2.57 heart:3.36 muscle:5.34 esophagus:3.38 stomach:- intestine:3.64 colon:3.76     liver/hepato:3.12    lung:2.69 bladder:2.92 kidney:4.59 pituitary:4.27 thyroid/parathyroid:4.98 adrenal gland:- pancreas:3.34 breast:3.80 salivary:5.90
RNA-seq uterus:- placenta:- prostate:3.28 ovary:3.94 testis:3.09 heart:2.33 muscle:6.54 esophagus:- stomach:- intestine:- colon:4.10     liver/hepato:2.20        lung:1.22    bladder:- kidney:4.84 pituitary:- thyroid/parathyroid:5.72 adrenal gland:3.28 pancreas:- breast:3.15 salivary:-

Gene Information

IDs

Refseq ID NM_022783
Gene ID 64798
Unigene ID Hs.112981
Probe set ID 218858_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000155792
GTEx ID ENSG00000155792

Orthologous Gene

Mouse[8]  NM_001037937, NM_145470
Rat[8]  NM_001037937, NM_145470

Chromosomal Region

8q24.12  [120,885,957  -  121,063,152]

Gene Family (Interpro ID)

IPR000591  DEP domain
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

8125298
11076863
11230166
11256614
12477932
14702039
15489336
16344560
16381901
19446321
20169205
20379614
20858096
21643629
21832049
21992080
22017875
22017876
22017877
22087225
22160218
22454292
23503641
23541542
23563706
23583980
23613505
23881914
23940030

Gene Ontology  (GO ID)

Biological Process

GO:0045792  negative regulation of cell size
GO:0006469  negative regulation of protein kinase activity
GO:0032007  negative regulation of TOR signaling pathway

Cellular Component

GO:0005622  intracellular

Molecular Function

GO:0005515  protein binding