purinergic receptor P2Y, G-protein coupled, 12

Synonym

P2T(AC), purinergic receptor P2Y, G-protein coupled, 12, ADP-glucose receptor, HORK3, P2Y(AC), P2Y purinoceptor 12, SP1999, P2RY12, P2Y12 platelet ADP receptor, P2Y(cyc), P2Y(ADP), P2Y12, ADPG-R

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:74.70

cerebellum:-

brain stem:-

corpus callosum/glia:233.30

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:11.80

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:40.30

bone:12.80

skin:4.80

GeneChip

nodata

CAGE

cerebrum:3.34

cerebellum:-

brain stem:4.51

corpus callosum/glia:4.54

pineal gland:2.53

peripheral nerve:-

spine:4.02

retina:-

eye:-

artery/aorta:1.03

vein:1.29

lymphnode:1.77

peripheral blood:-

spleen:2.20

thymus:0.54

bone marrow:-

adipose:3.10

bone:-

skin:-

RNA-seq

cerebrum:1.59

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.25

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.78

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:9.80

bladder:125.60

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:1.28

placenta:1.74

prostate:1.99

ovary:0.89

testis:0.85

heart:0.96

muscle:0.72

esophagus:1.50

stomach:-

intestine:1.66

colon:1.31

liver/hepato:1.47

lung:1.51

bladder:1.35

kidney:1.80

pituitary:0.90

thyroid/parathyroid:0.98

adrenal gland:-

pancreas:0

breast:1.68

salivary:1.00

RNA-seq

uterus:-

placenta:-

prostate:0.39

ovary:0.22

testis:0.56

heart:0.38

muscle:0.29

esophagus:-

stomach:-

intestine:-

colon:1.35

liver/hepato:0.66

lung:0.84

bladder:-

kidney:0.52

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:1.02

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_176876
Gene ID	64805
Unigene ID	Hs.591281
Probe set ID	-
Ensembl ID	ENSG00000169313
GTEx ID	ENSG00000169313

Orthologous Gene

Mouse[1]	NM_027571
Rat[1]	NM_022800

Chromosomal Region

3q25.1 [151,055,168 - 151,102,600]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily
IPR002286	P2 purinoceptor
IPR005394	P2Y12 purinoceptor
IPR008109	P2Y13 purinoceptor
IPR005466	UDP-glucose receptor

Gene Ontology (GO ID)

Biological Process

GO:0007596	blood coagulation
GO:0070588	calcium ion transmembrane transport
GO:0030030	cell projection organization
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007599	hemostasis
GO:0045596	negative regulation of cell differentiation
GO:0010700	negative regulation of norepinephrine secretion
GO:0030168	platelet activation
GO:0070527	platelet aggregation
GO:0043270	positive regulation of ion transport
GO:0043491	protein kinase B signaling cascade
GO:0051924	regulation of calcium ion transport

Cellular Component

GO:0009925	basal plasma membrane
GO:0005901	caveola
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0001609	adenosine receptor activity, G-protein coupled
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0001621	platelet ADP receptor activity

purinergic receptor P2Y, G-protein coupled, 12

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function