ST3 beta-galactoside alpha-2,3-sialyltransferase 4

 jump to detail

Synonym

SAT3, NANTA3, ST3GalIV, CGS23, ST3Gal III, ST3Gal IV, ST3GAL4, FLJ11867, Alpha 2,3-sialyltransferase IV, SIAT4C, ST-4, SAT-3, STZ, SIAT4, SIAT4-C, ST3 beta-galactoside alpha-2,3-sialyltransferase 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:32 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:224.60 retina:237.30 eye:52.90 artery/aorta:60 vein:- lymphnode:- peripheral blood:36.40 spleen:18.90 thymus:- bone marrow:- adipose:121 bone:- skin:52.80
GeneChip cerebrum:6.41 cerebellum:6.39 brain stem:6.56 corpus callosum/glia:6.70 pineal gland:- peripheral nerve:6.16 spine:6.20 retina:- eye:- artery/aorta:6.16 vein:6.50 lymphnode:6.31 peripheral blood:- spleen:6.20 thymus:5.34 bone marrow:6.21 adipose:6.20 bone:- skin:6.07
CAGE cerebrum:2.87 cerebellum:- brain stem:3.52 corpus callosum/glia:3.97 pineal gland:2.94 peripheral nerve:- spine:3.47 retina:- eye:- artery/aorta:3.31 vein:2.80 lymphnode:2.87 peripheral blood:- spleen:3.52 thymus:1.58 bone marrow:- adipose:2.45 bone:- skin:-
RNA-seq cerebrum:0.26 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.87 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:306 prostate:22.50 ovary:111.80 testis:30.30 heart:12.80 muscle:- esophagus:342.80 stomach:21.20 intestine:32.40 colon:84.80     liver/hepato:10.60        lung:24.40    bladder:- kidney:10.40 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:328.40
GeneChip uterus:6.19 placenta:7.44 prostate:5.91 ovary:6.72 testis:6.74 heart:6.54 muscle:6.22 esophagus:6.74 stomach:6.03 intestine:6.10 colon:6.65 liver/hepato:6.30 lung:6.40 bladder:- kidney:6.71 pituitary:6.24 thyroid/parathyroid:5.84 adrenal gland:7.62 pancreas:6.30 breast:6.02 salivary:6.23
CAGE uterus:2.56 placenta:4.90 prostate:3.24 ovary:4.35 testis:3.78 heart:3.48 muscle:0.79 esophagus:3.31 stomach:- intestine:1.55 colon:2.94     liver/hepato:3.01    lung:3.16 bladder:3.48 kidney:3.19 pituitary:2.12 thyroid/parathyroid:2.53 adrenal gland:- pancreas:1.74 breast:3.27 salivary:2.50
RNA-seq uterus:- placenta:- prostate:0.63 ovary:2.27 testis:1.30 heart:0.47 muscle:0.18 esophagus:- stomach:- intestine:- colon:0.67     liver/hepato:0.80        lung:0.99    bladder:- kidney:1.12 pituitary:- thyroid/parathyroid:0.29 adrenal gland:0.62 pancreas:- breast:0.60 salivary:-

Gene Information

IDs

Refseq ID NM_006278
Gene ID 6484
Unigene ID Hs.591947
Probe set ID 203759_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000110080
GTEx ID ENSG00000110080

Orthologous Gene

Mouse[1]  NM_009178
Rat[1]  NM_203337

Chromosomal Region

11q24.2  [126,225,535  -  126,310,239]

Gene Family (Interpro ID)

IPR001675  Glycosyl transferase, family 29
IPR012163  Sialyltransferase

Link to Pubmed  (Pubmed ID)

2187500
2541446
2542563
2649653
2829950
7588599
7655169
7901202
8288606
8557707
8611500
12375029
12441665
12459555
12477932
12565846
14702039
15342556
15489334
16169070
16344560
17054948
19520807
19781661
19946888
20237496
20379614
20383541
20686565
21140242
21378990
21906983
21963094
22001757
22691873
23726834
23799130
24097068

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0044267  cellular protein metabolic process
GO:0030203  glycosaminoglycan metabolic process
GO:0018146  keratan sulfate biosynthetic process
GO:0042339  keratan sulfate metabolic process
GO:0016266  O-glycan processing
GO:0043687  post-translational protein modification
GO:0018279  protein amino acid N-linked glycosylation via asparagine

Cellular Component

GO:0005576  extracellular region
GO:0032580  Golgi cisterna membrane
GO:0000139  Golgi membrane
GO:0030173  integral to Golgi membrane

Molecular Function

GO:0003836  beta-galactoside alpha-2,3-sialyltransferase activity
GO:0047288  monosialoganglioside sialyltransferase activity