solute carrier family 26, member 6

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Synonym

Solute carrier family 26 member 6, SLC26A6, DKFZp586E1422, Pendrin-like protein 1, Pendrin L1, solute carrier family 26, member 6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:76.40 artery/aorta:- vein:- lymphnode:- peripheral blood:18.20 spleen:94.50 thymus:12.90 bone marrow:137.80 adipose:- bone:12.80 skin:19.20
GeneChip cerebrum:4.65 cerebellum:4.71 brain stem:4.55 corpus callosum/glia:4.78 pineal gland:- peripheral nerve:4.85 spine:4.63 retina:- eye:- artery/aorta:5.78 vein:4.74 lymphnode:5.29 peripheral blood:- spleen:5.06 thymus:5.07 bone marrow:5.44 adipose:4.95 bone:- skin:4.93
CAGE cerebrum:1.72 cerebellum:- brain stem:2.08 corpus callosum/glia:2.01 pineal gland:1.60 peripheral nerve:- spine:2.02 retina:- eye:- artery/aorta:2.62 vein:1.57 lymphnode:2.06 peripheral blood:- spleen:2.03 thymus:1.97 bone marrow:- adipose:1.86 bone:- skin:-
RNA-seq cerebrum:0.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.63 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.80 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:- prostate:11.30 ovary:- testis:17.30 heart:12.80 muscle:20.10 esophagus:- stomach:42.50 intestine:97.20 colon:93.30     liver/hepato:-        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:- salivary:-
GeneChip uterus:5.03 placenta:5.05 prostate:4.89 ovary:4.80 testis:4.92 heart:4.95 muscle:4.95 esophagus:4.99 stomach:5.61 intestine:5.20 colon:5.73 liver/hepato:5.11 lung:5.25 bladder:- kidney:6.09 pituitary:4.96 thyroid/parathyroid:4.97 adrenal gland:5.46 pancreas:5 breast:5.02 salivary:4.86
CAGE uterus:2.03 placenta:1.94 prostate:2.05 ovary:1.65 testis:2.07 heart:1.83 muscle:1.46 esophagus:2.00 stomach:- intestine:2.97 colon:3.39     liver/hepato:1.47    lung:2.07 bladder:1.47 kidney:2.24 pituitary:1.65 thyroid/parathyroid:1.48 adrenal gland:- pancreas:2.71 breast:2.02 salivary:2.12
RNA-seq uterus:- placenta:- prostate:0.89 ovary:0.88 testis:1.38 heart:0.46 muscle:1.51 esophagus:- stomach:- intestine:- colon:1.61     liver/hepato:0.79        lung:0.98    bladder:- kidney:1.61 pituitary:- thyroid/parathyroid:0.75 adrenal gland:0.00 pancreas:- breast:0.60 salivary:-

Gene Information

IDs

Refseq ID NM_134263
Gene ID 65010
Unigene ID Hs.631925
Probe set ID 221572_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000225697
GTEx ID ENSG00000225697

Orthologous Gene

Mouse[1]  NM_134420
Rat[1]  NM_001143817

Chromosomal Region

3p21.31  [48,663,156  -  48,672,926]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10610771
11087667
11247665
11581495
12217875
12444019
12477932
14531806
14702039
15489334
15548529
15956810
15990874
16344560
16606687
17081983
17120764
17881426
18174209
18655181
18951670
19029225
19367581
19910524
20501439
21906983
21963094
21987572
22053931
24647542

Gene Ontology  (GO ID)

Biological Process

GO:0015701  bicarbonate transport
GO:0071320  cellular response to cAMP
GO:0071332  cellular response to fructose stimulus
GO:0071346  cellular response to interferon-gamma
GO:0006821  chloride transport
GO:0042045  epithelial fluid transport
GO:0015724  formate transport
GO:0050892  intestinal absorption
GO:0051454  intracellular pH elevation
GO:0006811  ion transport
GO:0015797  mannitol transport
GO:0019532  oxalate transport
GO:0046724  oxalic acid secretion
GO:0070528  protein kinase C signaling cascade
GO:0051453  regulation of intracellular pH
GO:0048240  sperm capacitation
GO:0008272  sulfate transport
GO:0030321  transepithelial chloride transport
GO:0070633  transepithelial transport
GO:0055085  transmembrane transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0031526  brush border membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0031988  membrane-bounded vesicle
GO:0005886  plasma membrane
GO:0012506  vesicle membrane

Molecular Function

GO:0015301  anion:anion antiporter activity
GO:0015106  bicarbonate transmembrane transporter activity
GO:0015108  chloride transmembrane transporter activity
GO:0015562  efflux transmembrane transporter activity
GO:0015660  formate efflux transmembrane transporter activity
GO:0015499  formate transmembrane transporter activity
GO:0015659  formate uptake transmembrane transporter activity
GO:0019531  oxalate transmembrane transporter activity
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0008271  secondary active sulfate transmembrane transporter activity
GO:0015116  sulfate transmembrane transporter activity