solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1

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Synonym

CSNU1, B(0,+)-type amino acid transport protein, ATR1, SLC3A1, D2H, RBAT, NBAT, FLJ34681

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:27.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:3.77 cerebellum:3.78 brain stem:3.74 corpus callosum/glia:3.49 pineal gland:- peripheral nerve:3.30 spine:3.41 retina:- eye:- artery/aorta:3.73 vein:3.43 lymphnode:3.20 peripheral blood:- spleen:3.16 thymus:3.03 bone marrow:3.23 adipose:3.39 bone:- skin:3.27
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.18 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.06 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.03 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:18.20 prostate:11.30 ovary:- testis:17.30 heart:- muscle:20.10 esophagus:- stomach:- intestine:129.60 colon:17     liver/hepato:63.30        lung:-    bladder:251.20 kidney:1559.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.78 placenta:3.22 prostate:3.85 ovary:3.28 testis:3.61 heart:3.46 muscle:3.31 esophagus:3.18 stomach:3.34 intestine:6.69 colon:4.09 liver/hepato:5.10 lung:3.10 bladder:- kidney:10.82 pituitary:3.43 thyroid/parathyroid:3.14 adrenal gland:3.15 pancreas:9.23 breast:3.20 salivary:3.07
CAGE uterus:1.13 placenta:0.85 prostate:0 ovary:0.07 testis:0.66 heart:0 muscle:0 esophagus:0.09 stomach:- intestine:5.46 colon:3.49     liver/hepato:2.72    lung:0 bladder:0.09 kidney:6.52 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:4.73 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.27 ovary:0.07 testis:1.16 heart:0.03 muscle:0 esophagus:- stomach:- intestine:- colon:0.32     liver/hepato:2.30        lung:0.04    bladder:- kidney:6.49 pituitary:- thyroid/parathyroid:0.09 adrenal gland:0.10 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_000341
Gene ID 6519
Unigene ID Hs.112916
Probe set ID 205799_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000138079
GTEx ID ENSG00000138079

Orthologous Gene

Mouse[1]  NM_009205
Rat [0]  

Chromosomal Region

2p21  [44,502,599  -  44,548,633]

Gene Family (Interpro ID)

IPR017853  Glycoside hydrolase, catalytic core
IPR013781  Glycoside hydrolase, subgroup, catalytic core
IPR006047  Glycosyl hydrolase, family 13, catalytic domain
IPR006589  Glycosyl hydrolase, family 13, subfamily, catalytic domain

Link to Pubmed  (Pubmed ID)

7539209
7568194
7573036
7575432
7686906
7789946
8054986
8125298
8486766
8663184
9186880
10574970
10588648
10799513
11318953
11458794
11748844
12060600
12167606
12234283
12239244
12372889
12477932
12820697
14531788
14561219
14702039
14991253
15489334
15635077
15691362
15815621
15818800
15818801
15818802
15913950
16138908
16358225
17010017
18195088
18234729
18332091
18752446
18778962
19056867
19782624
20146678
20800603
21255007
22796000
23794250

Gene Ontology  (GO ID)

Biological Process

GO:0003333  amino acid transmembrane transport
GO:0006865  amino acid transport
GO:0015802  basic amino acid transport
GO:0005975  carbohydrate metabolic process
GO:0006520  cellular amino acid metabolic process
GO:0006811  ion transport
GO:0015811  L-cystine transport
GO:0055085  transmembrane transport

Cellular Component

GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005743  mitochondrial inner membrane
GO:0005886  plasma membrane
GO:0005774  vacuolar membrane

Molecular Function

GO:0015171  amino acid transmembrane transporter activity
GO:0015174  basic amino acid transmembrane transporter activity
GO:0003824  catalytic activity
GO:0043169  cation binding
GO:0015184  L-cystine transmembrane transporter activity
GO:0046982  protein heterodimerization activity