solute carrier family 5 (sodium/myo-inositol cotransporter), member 3

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Synonym

SLC5A3, Sodium/myo-inositol cotransporter, SMIT2, Na(+)/myo-inositol cotransporter, SMIT

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:171.80 cerebellum:63 brain stem:6535.90 corpus callosum/glia:- pineal gland:296.70 peripheral nerve:276 spine:112.30 retina:237.30 eye:158.70 artery/aorta:30 vein:- lymphnode:60.70 peripheral blood:36.40 spleen:75.60 thymus:103.10 bone marrow:19.70 adipose:121 bone:51.20 skin:168
GeneChip cerebrum:6.40 cerebellum:5.88 brain stem:6.55 corpus callosum/glia:5.94 pineal gland:- peripheral nerve:8.14 spine:6.65 retina:- eye:- artery/aorta:7.64 vein:6.57 lymphnode:6.85 peripheral blood:- spleen:6.53 thymus:7.48 bone marrow:6.03 adipose:7.17 bone:- skin:6.59
CAGE nodata
RNA-seq cerebrum:1.77 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.83 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:164 placenta:91.10 prostate:67.60 ovary:37.30 testis:82.20 heart:166 muscle:80.40 esophagus:- stomach:106.20 intestine:- colon:101.80     liver/hepato:95        lung:136.90    bladder:- kidney:207.90 pituitary:- thyroid/parathyroid:655 adrenal gland:152.40 pancreas:35.60 breast:111.50 salivary:-
GeneChip uterus:7.53 placenta:6.79 prostate:6.94 ovary:7.48 testis:7.68 heart:5.81 muscle:5.32 esophagus:5.84 stomach:6.73 intestine:5.94 colon:6.08 liver/hepato:7.07 lung:6.65 bladder:- kidney:9.77 pituitary:7.27 thyroid/parathyroid:10.16 adrenal gland:7.68 pancreas:4.16 breast:6.98 salivary:6.01
CAGE nodata
RNA-seq uterus:- placenta:- prostate:2.29 ovary:2.51 testis:3.13 heart:0.90 muscle:0.82 esophagus:- stomach:- intestine:- colon:2.94     liver/hepato:1.65        lung:1.76    bladder:- kidney:4.62 pituitary:- thyroid/parathyroid:4.64 adrenal gland:1.73 pancreas:- breast:3.04 salivary:-

Gene Information

IDs

Refseq ID NM_006933
Gene ID 6526
Unigene ID Hs.302742
Probe set ID 212944_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198743
GTEx ID ENSG00000198743

Orthologous Gene

Mouse[2]  NM_017391
Rat [0]  

Chromosomal Region

21q22.11  [35,445,870  -  35,478,559]

Gene Family (Interpro ID)

IPR001734  Sodium/solute symporter
IPR019900  Sodium/solute symporter, subgroup

Link to Pubmed  (Pubmed ID)

1372904
7789985
8646889
9441750
9612208
9685419
10830953
14702039
15342556
16344560
17178845
19032932
19198609
19738201
20738937
20971364
21139048
21565611
21906983
21963094
22053931
23207989

Gene Ontology  (GO ID)

Biological Process

GO:0006020  inositol metabolic process
GO:0007422  peripheral nervous system development
GO:0043576  regulation of respiratory gaseous exchange
GO:0055085  transmembrane transport
GO:0006810  transport

Cellular Component

GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005367  myo-inositol:sodium symporter activity