solute carrier family 6 (neurotransmitter transporter, GABA), member 13

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Synonym

GAT2, SLC6A13, Sodium- and chloride-dependent GABA transporter 2, GAT-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:55.70 cerebellum:37.80 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:105.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:6.32 cerebellum:6.17 brain stem:6.38 corpus callosum/glia:6.13 pineal gland:- peripheral nerve:6.24 spine:6.38 retina:- eye:- artery/aorta:6.21 vein:6.29 lymphnode:6.14 peripheral blood:- spleen:5.88 thymus:5.75 bone marrow:6.39 adipose:6.23 bone:- skin:5.98
CAGE cerebrum:1.85 cerebellum:- brain stem:2.34 corpus callosum/glia:2.21 pineal gland:2.54 peripheral nerve:- spine:2.12 retina:- eye:- artery/aorta:0.34 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.62 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:21.10        lung:4.90    bladder:- kidney:696.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.84 placenta:6.03 prostate:5.82 ovary:5.87 testis:6.04 heart:6.29 muscle:6.42 esophagus:6.07 stomach:6.16 intestine:6.32 colon:6.55 liver/hepato:6.64 lung:6.28 bladder:- kidney:7.54 pituitary:6.20 thyroid/parathyroid:6.02 adrenal gland:6.05 pancreas:6.55 breast:5.77 salivary:6.30
CAGE uterus:0 placenta:0.08 prostate:0 ovary:0.37 testis:0.04 heart:0 muscle:0.05 esophagus:0 stomach:- intestine:0.43 colon:0.38     liver/hepato:1.44    lung:0.64 bladder:0 kidney:4.54 pituitary:1.34 thyroid/parathyroid:2.73 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.11 testis:0.07 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.00        lung:0.13    bladder:- kidney:3.29 pituitary:- thyroid/parathyroid:1.18 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_016615
Gene ID 6540
Unigene ID Hs.504398
Probe set ID 207184_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000010379
GTEx ID ENSG00000010379

Orthologous Gene

Mouse[1]  NM_144512
Rat [0]  

Chromosomal Region

12p13.33  [329,789  -  372,039]

Gene Family (Interpro ID)

IPR000175  Sodium:neurotransmitter symporter
IPR002981  Sodium:neurotransmitter symporter, GABA, GAT-2

Link to Pubmed  (Pubmed ID)

1400419
8889548
11824941
12477932
15252450
16125675
16344560
17502375
19056867
19086053
19450549
19874574
19913121
20379614
20383146
20398908
20424473
20628086
22932902
23275563
23378610

Gene Ontology  (GO ID)

Biological Process

GO:0007269  neurotransmitter secretion
GO:0007268  synaptic transmission
GO:0055085  transmembrane transport

Cellular Component

GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005332  gamma-aminobutyric acid:sodium symporter activity
GO:0042165  neurotransmitter binding
GO:0005328  neurotransmitter:sodium symporter activity