solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

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Synonym

Ecotropic retroviral leukemia receptor homolog, Ecotropic retrovirus receptor homolog, CAT-1, ERR, REC1L, SLC7A1, High-affinity cationic amino acid transporter 1, HCAT1, System Y+ basic amino acid transporter, ATRC1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:67.60 cerebellum:63 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:224.60 retina:- eye:82.30 artery/aorta:- vein:66.60 lymphnode:50.60 peripheral blood:36.40 spleen:56.70 thymus:51.50 bone marrow:39.40 adipose:- bone:25.60 skin:57.60
GeneChip cerebrum:7.99 cerebellum:7.66 brain stem:8.41 corpus callosum/glia:7.76 pineal gland:- peripheral nerve:7.97 spine:8.24 retina:- eye:- artery/aorta:7.11 vein:6.97 lymphnode:7.24 peripheral blood:- spleen:6.84 thymus:7.21 bone marrow:8.06 adipose:6.59 bone:- skin:8.32
CAGE cerebrum:2.96 cerebellum:- brain stem:3.54 corpus callosum/glia:3.29 pineal gland:3.16 peripheral nerve:- spine:2.97 retina:- eye:- artery/aorta:2.70 vein:2.80 lymphnode:3.15 peripheral blood:- spleen:2.71 thymus:2.49 bone marrow:- adipose:2.43 bone:- skin:-
RNA-seq cerebrum:3.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:118.50 placenta:58.30 prostate:22.50 ovary:- testis:43.30 heart:25.50 muscle:- esophagus:- stomach:127.50 intestine:- colon:118.70     liver/hepato:63.30        lung:19.60    bladder:- kidney:41.60 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:17.80 breast:74.30 salivary:-
GeneChip uterus:7.38 placenta:7.15 prostate:8.09 ovary:7.34 testis:8.05 heart:6.45 muscle:5.68 esophagus:9.14 stomach:7.52 intestine:7.67 colon:7.65 liver/hepato:5.10 lung:5.80 bladder:- kidney:6.58 pituitary:7.42 thyroid/parathyroid:6.91 adrenal gland:7.07 pancreas:8.63 breast:7.54 salivary:8.42
CAGE uterus:2.38 placenta:3.34 prostate:2.34 ovary:2.67 testis:2.97 heart:2.30 muscle:1.46 esophagus:3.91 stomach:- intestine:2.88 colon:2.87     liver/hepato:1.37    lung:2.06 bladder:2.43 kidney:1.99 pituitary:2.27 thyroid/parathyroid:2.22 adrenal gland:- pancreas:3.99 breast:2.41 salivary:3.40
RNA-seq uterus:- placenta:- prostate:2.59 ovary:3.39 testis:2.54 heart:1.66 muscle:1.16 esophagus:- stomach:- intestine:- colon:2.66     liver/hepato:0.31        lung:2.03    bladder:- kidney:2.34 pituitary:- thyroid/parathyroid:2.89 adrenal gland:3.08 pancreas:- breast:1.75 salivary:-

Gene Information

IDs

Refseq ID NM_003045
Gene ID 6541
Unigene ID Hs.14846
Probe set ID 212295_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000139514
GTEx ID ENSG00000139514

Orthologous Gene

Mouse[1]  NM_007513
Rat [0]  

Chromosomal Region

13q12.3  [30,083,547  -  30,169,721]

Gene Family (Interpro ID)

IPR002293  Amino acid/polyamine transporter I
IPR004755  Cationic amino acid transport permease
IPR015606  Cationic amino acid transporter

Link to Pubmed  (Pubmed ID)

1348489
1718082
10485994
11665818
11891586
12202949
12388095
12477932
12787129
14702039
15057823
15064952
15086470
15342556
15489334
15491978
15631944
16344560
16751776
17325243
17494634
18172665
18195088
18574322
19067360
19322201
19946888
21139048
21212261
21302286
21308737
21722652
21832049
21890473
21906983
21923750
21987572
22053931
22505724
22705145
22870827
23000965
23009292
23824909
24040099
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006865  amino acid transport
GO:0006811  ion transport
GO:0055085  transmembrane transport
GO:0006810  transport

Cellular Component

GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0015181  arginine transmembrane transporter activity