solute carrier family 8 (sodium/calcium exchanger), member 2

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Synonym

Na(+)/Ca(2+)-exchange protein 2, NCX2, Sodium/calcium exchanger 2 precursor, KIAA1087, SLC8A2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:69.90 cerebellum:365.20 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.80 cerebellum:7.89 brain stem:6.09 corpus callosum/glia:6.16 pineal gland:- peripheral nerve:5.70 spine:6.06 retina:- eye:- artery/aorta:5.59 vein:6.12 lymphnode:5.58 peripheral blood:- spleen:5.50 thymus:5.33 bone marrow:6.13 adipose:5.67 bone:- skin:5.68
CAGE cerebrum:4.29 cerebellum:- brain stem:1.86 corpus callosum/glia:2.70 pineal gland:4.49 peripheral nerve:- spine:2.08 retina:- eye:- artery/aorta:1.38 vein:0.59 lymphnode:0 peripheral blood:- spleen:0 thymus:0.12 bone marrow:- adipose:0.36 bone:- skin:-
RNA-seq cerebrum:3.51 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.07 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.04 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:3.60 prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:- salivary:-
GeneChip uterus:5.78 placenta:6.02 prostate:5.16 ovary:5.31 testis:5.77 heart:5.81 muscle:5.75 esophagus:5.76 stomach:5.76 intestine:5.75 colon:6.03 liver/hepato:5.83 lung:5.69 bladder:- kidney:5.53 pituitary:6.88 thyroid/parathyroid:5.25 adrenal gland:5.66 pancreas:6.22 breast:5.20 salivary:5.64
CAGE uterus:1.99 placenta:0 prostate:1.56 ovary:0.72 testis:0.89 heart:0.23 muscle:0.30 esophagus:1.29 stomach:- intestine:1.33 colon:2.15     liver/hepato:0    lung:0 bladder:2.19 kidney:0 pituitary:2.54 thyroid/parathyroid:0 adrenal gland:- pancreas:2.41 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:1.58 ovary:0.26 testis:0.98 heart:0.01 muscle:0.06 esophagus:- stomach:- intestine:- colon:1.37     liver/hepato:0.00        lung:0.03    bladder:- kidney:0.01 pituitary:- thyroid/parathyroid:0.04 adrenal gland:0.06 pancreas:- breast:0.03 salivary:-

Gene Information

IDs

Refseq ID NM_015063
Gene ID 6543
Unigene ID Hs.172884
Probe set ID 215267_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118160
GTEx ID ENSG00000118160

Orthologous Gene

Mouse[1]  NM_148946
Rat [0]  

Chromosomal Region

19q13.32  [47,931,279  -  47,975,307]

Gene Family (Interpro ID)

IPR004836  Sodium/calcium exchanger protein

Link to Pubmed  (Pubmed ID)

8021246
10470851
15557343
16679322
19913121
20132488
20628086
21382638
21858195
23224884
23224887
23224890

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0007154  cell communication
GO:0006811  ion transport
GO:0055085  transmembrane transport

Cellular Component

GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005432  calcium:sodium antiporter activity
GO:0005516  calmodulin binding