solute carrier family 7 (cationic amino acid transporter, y+ system), member 4

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Synonym

SLC7A4, MGC129977, CAT4, Cationic amino acid transporter 4, HCAT3, MGC129976, VH, CAT-4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:5.12 cerebellum:5.05 brain stem:5.36 corpus callosum/glia:4.88 pineal gland:- peripheral nerve:4.74 spine:4.67 retina:- eye:- artery/aorta:5.08 vein:4.90 lymphnode:4.82 peripheral blood:- spleen:4.70 thymus:4.78 bone marrow:4.94 adipose:5.09 bone:- skin:5.07
CAGE cerebrum:1.16 cerebellum:- brain stem:0.56 corpus callosum/glia:0.43 pineal gland:0 peripheral nerve:- spine:0.17 retina:- eye:- artery/aorta:0.47 vein:0.34 lymphnode:0.86 peripheral blood:- spleen:0.09 thymus:0.18 bone marrow:- adipose:1.12 bone:- skin:-
RNA-seq cerebrum:0.73 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.49 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.16 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:25.50 prostate:- ovary:- testis:13 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.91 placenta:4.32 prostate:5.16 ovary:4.82 testis:5.19 heart:4.87 muscle:5.26 esophagus:4.88 stomach:4.67 intestine:4.99 colon:5.16 liver/hepato:4.77 lung:4.81 bladder:- kidney:4.94 pituitary:5.21 thyroid/parathyroid:4.93 adrenal gland:5 pancreas:5.52 breast:4.72 salivary:4.93
CAGE uterus:0.48 placenta:2.75 prostate:0.27 ovary:0.32 testis:3.06 heart:0.09 muscle:0 esophagus:0.94 stomach:- intestine:0.33 colon:0.04     liver/hepato:0.26    lung:0.27 bladder:0.26 kidney:0.08 pituitary:1.00 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:1.36 salivary:1.67
RNA-seq uterus:- placenta:- prostate:0.71 ovary:0.42 testis:2.29 heart:0.01 muscle:0.07 esophagus:- stomach:- intestine:- colon:0.09     liver/hepato:0.13        lung:0.34    bladder:- kidney:0.11 pituitary:- thyroid/parathyroid:0.16 adrenal gland:0.17 pancreas:- breast:1.85 salivary:-

Gene Information

IDs

Refseq ID NM_004173
Gene ID 6545
Unigene ID Hs.197116
Probe set ID 214406_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000099960
GTEx ID ENSG00000099960

Orthologous Gene

Mouse[2]  NM_144852
Rat[1]  NM_001107078

Chromosomal Region

22q11.21  [21,383,007  -  21,387,129]

Gene Family (Interpro ID)

IPR002293  Amino acid/polyamine transporter I

Link to Pubmed  (Pubmed ID)

9598310
9754584
10700465
11665818
12049641
12477932
15461802
15489334
17051526
18460403
20452607
20584552
20685009

Gene Ontology  (GO ID)

Biological Process

GO:0015802  basic amino acid transport
GO:0006520  cellular amino acid metabolic process
GO:0006810  transport

Cellular Component

GO:0016021  integral to membrane

Molecular Function

GO:0015174  basic amino acid transmembrane transporter activity