bone morphogenetic protein 7

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Synonym

Eptotermin alfa, Osteogenic protein 1, OP1, BMP7, Bone morphogenetic protein 7 precursor, OP-1, BMP-7, BMP 7

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:47.40

cerebellum:37.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:61.30

spine:-

retina:118.60

eye:99.90

artery/aorta:-

vein:-

lymphnode:30.30

peripheral blood:-

spleen:-

thymus:38.70

bone marrow:-

adipose:-

bone:25.60

skin:14.40

GeneChip

cerebrum:6.96

cerebellum:6.15

brain stem:6.80

corpus callosum/glia:7.85

pineal gland:-

peripheral nerve:6.94

spine:7.63

retina:-

eye:-

artery/aorta:5.81

vein:5.95

lymphnode:5.64

peripheral blood:-

spleen:5.56

thymus:5.65

bone marrow:5.94

adipose:5.79

bone:-

skin:6.46

CAGE

cerebrum:3.33

cerebellum:-

brain stem:3.27

corpus callosum/glia:4.14

pineal gland:1.48

peripheral nerve:-

spine:3.44

retina:-

eye:-

artery/aorta:1.10

vein:1.53

lymphnode:1.56

peripheral blood:-

spleen:0.45

thymus:1.88

bone marrow:-

adipose:0.46

bone:-

skin:-

RNA-seq

cerebrum:3.33

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.37

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.45

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:76.50

prostate:90.10

ovary:37.30

testis:-

heart:114.90

muscle:-

esophagus:-

stomach:-

intestine:-

colon:59.40

liver/hepato:-

lung:9.80

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:18.60

salivary:-

GeneChip

uterus:5.74

placenta:6.86

prostate:5.95

ovary:5.73

testis:5.41

heart:6.21

muscle:6.04

esophagus:6.84

stomach:5.86

intestine:5.77

colon:5.96

liver/hepato:5.69

lung:5.56

bladder:-

kidney:6.05

pituitary:5.99

thyroid/parathyroid:8.31

adrenal gland:5.76

pancreas:5.84

breast:5.93

salivary:5.65

CAGE

uterus:1.93

placenta:3.55

prostate:2.54

ovary:1.23

testis:1.24

heart:1.41

muscle:0.09

esophagus:3.33

stomach:-

intestine:1.44

colon:1.28

liver/hepato:0

lung:0.64

bladder:1.69

kidney:1.17

pituitary:1.05

thyroid/parathyroid:3.90

adrenal gland:-

pancreas:0.58

breast:0

salivary:0.62

RNA-seq

uterus:-

placenta:-

prostate:2.25

ovary:0.92

testis:1.91

heart:1.95

muscle:0.09

esophagus:-

stomach:-

intestine:-

colon:1.54

liver/hepato:0.00

lung:0.84

bladder:-

kidney:1.48

pituitary:-

thyroid/parathyroid:4.28

adrenal gland:0.05

pancreas:-

breast:0.70

salivary:-

IDs

Refseq ID	NM_001719
Gene ID	655
Unigene ID	Hs.473163
Probe set ID	209590_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000101144
GTEx ID	ENSG00000101144

Orthologous Gene

Mouse[3]	NM_007557
Rat [0]

Chromosomal Region

20q13.31 [55,743,804 - 55,841,685]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002405	Inhibin, alpha subunit
IPR015615	Transforming growth factor-beta-related

Gene Ontology (GO ID)

Biological Process

GO:0007411	axon guidance
GO:0030509	BMP signaling pathway
GO:0060445	branching involved in salivary gland morphogenesis
GO:0048754	branching morphogenesis of a tube
GO:0051216	cartilage development
GO:0071456	cellular response to hypoxia
GO:0016358	dendrite development
GO:0048596	embryonic camera-type eye morphogenesis
GO:0030326	embryonic limb morphogenesis
GO:0009880	embryonic pattern specification
GO:0060272	embryonic skeletal joint morphogenesis
GO:0030855	epithelial cell differentiation
GO:0001837	epithelial to mesenchymal transition
GO:0030198	extracellular matrix organization
GO:0040007	growth
GO:0048762	mesenchymal cell differentiation
GO:0060485	mesenchyme development
GO:0001707	mesoderm formation
GO:0001823	mesonephros development
GO:0001656	metanephros development
GO:0070487	monocyte aggregation
GO:0045786	negative regulation of cell cycle
GO:0060548	negative regulation of cell death
GO:0043407	negative regulation of MAP kinase activity
GO:0045839	negative regulation of mitosis
GO:0050768	negative regulation of neurogenesis
GO:0045665	negative regulation of neuron differentiation
GO:0042347	negative regulation of NF-kappaB import into nucleus
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0045746	negative regulation of Notch signaling pathway
GO:0042326	negative regulation of phosphorylation
GO:0060686	negative regulation of prostatic bud formation
GO:0010664	negative regulation of striated muscle cell apoptosis
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048812	neuron projection morphogenesis
GO:0042475	odontogenesis of dentine-containing tooth
GO:0001503	ossification
GO:0043065	positive regulation of apoptosis
GO:0030501	positive regulation of bone mineralization
GO:0034116	positive regulation of heterotypic cell-cell adhesion
GO:0045666	positive regulation of neuron differentiation
GO:0045669	positive regulation of osteoblast differentiation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0034504	protein localization in nucleus
GO:0060687	regulation of branching involved in prostate gland morphogenesis
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
GO:0001501	skeletal system development
GO:0060395	SMAD protein signal transduction
GO:0043401	steroid hormone mediated signaling pathway
GO:0001657	ureteric bud development

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space

Molecular Function

GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0005515	protein binding

bone morphogenetic protein 7

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function