solute carrier family 10 (sodium/bile acid cotransporter family), member 2

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Synonym

Na(+)-dependent ileal bile acid transporter, NTCP2, Ileal Na(+)/bile acid cotransporter, Apical sodium-dependent bile acid transporter, Solute carrier family 10 member 2, SLC10A2, Ileal sodium-dependent bile acid transporter, Ileal sodium/bile acid cotransporter, ASBT, IBAT, ISBT

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.72 cerebellum:3.78 brain stem:3.86 corpus callosum/glia:3.72 pineal gland:- peripheral nerve:3.73 spine:3.67 retina:- eye:- artery/aorta:3.67 vein:3.73 lymphnode:3.61 peripheral blood:- spleen:3.53 thymus:3.58 bone marrow:3.66 adipose:3.64 bone:- skin:3.71
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0.09 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:64.80 colon:-     liver/hepato:-        lung:-    bladder:- kidney:145.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.48 placenta:3.66 prostate:3.53 ovary:3.49 testis:3.37 heart:3.77 muscle:3.96 esophagus:3.46 stomach:3.64 intestine:4.42 colon:3.86 liver/hepato:3.74 lung:3.63 bladder:- kidney:5.16 pituitary:3.63 thyroid/parathyroid:3.40 adrenal gland:3.60 pancreas:3.65 breast:3.51 salivary:3.56
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:3.93 colon:0.46     liver/hepato:0    lung:0 bladder:0 kidney:1.72 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0.01    bladder:- kidney:1.18 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_000452
Gene ID 6555
Unigene ID Hs.194783
Probe set ID 207095_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125255
GTEx ID ENSG00000125255

Orthologous Gene

Mouse[1]  NM_011388
Rat [0]  

Chromosomal Region

13q33.1  [103,696,350  -  103,719,196]

Gene Family (Interpro ID)

IPR004710  Bile acid transporter
IPR002657  Bile acid:sodium symporter

Link to Pubmed  (Pubmed ID)

7592981
8661017
9109432
9458785
11396803
11535543
11589382
11742882
12055195
12220224
12364586
12477932
15057823
15239098
15304498
15350125
15952798
16230354
16237211
16411770
16541252
16749855
16749860
16899538
17942302
17960397
18028035
18063707
18311924
18508772
18644122
18668439
18688880
19184108
19653651
19823678
20056894
20201924
20346360
20453000
20600720
20616306
21341987
21526375
21646357
21649730
21829377
22016432
22093174
22403793
22669917
22960999
24045943
24498857

Gene Ontology  (GO ID)

Biological Process

GO:0015721  bile acid and bile salt transport
GO:0008206  bile acid metabolic process
GO:0006810  transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0005887  integral to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0000502  proteasome complex

Molecular Function

GO:0008508  bile acid:sodium symporter activity