solute carrier family 22 (organic cation/carnitine transporter), member 5

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Synonym

OCTN2, FLJ46769, SLC22A5, Solute carrier family 22 member 5, CDSP, Organic cation/carnitine transporter 2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:19

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:61.30

spine:-

retina:-

eye:47

artery/aorta:-

vein:-

lymphnode:20.20

peripheral blood:18.20

spleen:-

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:9.60

GeneChip

cerebrum:5.56

cerebellum:6.41

brain stem:5.38

corpus callosum/glia:5.77

pineal gland:-

peripheral nerve:5.91

spine:6.06

retina:-

eye:-

artery/aorta:6.14

vein:5.49

lymphnode:5.44

peripheral blood:-

spleen:5.36

thymus:5.12

bone marrow:5.20

adipose:5.73

bone:-

skin:5.66

CAGE

cerebrum:2.41

cerebellum:-

brain stem:1.83

corpus callosum/glia:2.23

pineal gland:2.63

peripheral nerve:-

spine:2.29

retina:-

eye:-

artery/aorta:2.46

vein:2.01

lymphnode:1.66

peripheral blood:-

spleen:1.02

thymus:1.14

bone marrow:-

adipose:1.69

bone:-

skin:-

RNA-seq

cerebrum:1.63

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.87

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.24

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:36.40

prostate:11.30

ovary:-

testis:26

heart:38.30

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:42.40

liver/hepato:-

lung:24.40

bladder:125.60

kidney:83.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:37.20

salivary:-

GeneChip

uterus:6.16

placenta:7.37

prostate:7.18

ovary:6.44

testis:5.53

heart:6.23

muscle:6.79

esophagus:5.70

stomach:6.05

intestine:6.56

colon:6.49

liver/hepato:5.97

lung:5.58

bladder:-

kidney:8.52

pituitary:6.60

thyroid/parathyroid:6.45

adrenal gland:6.19

pancreas:5.56

breast:6.44

salivary:6.26

CAGE

uterus:2.04

placenta:2.84

prostate:2.58

ovary:2.04

testis:2.07

heart:2.52

muscle:4.76

esophagus:1.68

stomach:-

intestine:3.77

colon:3.24

liver/hepato:1.95

lung:1.72

bladder:2.13

kidney:4.51

pituitary:2.93

thyroid/parathyroid:2.43

adrenal gland:-

pancreas:2.48

breast:2.41

salivary:2.26

RNA-seq

uterus:-

placenta:-

prostate:2.88

ovary:2.50

testis:2.10

heart:2.30

muscle:3.81

esophagus:-

stomach:-

intestine:-

colon:1.90

liver/hepato:1.54

lung:1.48

bladder:-

kidney:5.63

pituitary:-

thyroid/parathyroid:2.51

adrenal gland:1.38

pancreas:-

breast:2.63

salivary:-

IDs

Refseq ID	NM_003060
Gene ID	6584
Unigene ID	Hs.443572
Probe set ID	205074_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000197375
GTEx ID	ENSG00000197375

Orthologous Gene

Mouse[4]	NM_011396, NM_019723
Rat [0]

Chromosomal Region

5q31.1 [131,705,444 - 131,731,306]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR020846	Major facilitator superfamily
IPR011701	Major facilitator superfamily MFS-1
IPR016196	Major facilitator superfamily, general substrate transporter
IPR004749	Organic cation transport protein

Gene Ontology (GO ID)

Biological Process

GO:0015879	carnitine transport
GO:0015893	drug transport
GO:0006855	multidrug transport
GO:0060731	positive regulation of intestinal epithelial structure maintenance
GO:0015697	quaternary ammonium group transport
GO:0052106	quorum sensing during interaction with host
GO:0006814	sodium ion transport
GO:0070715	sodium-dependent organic cation transport
GO:0055085	transmembrane transport

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0031526	brush border membrane
GO:0016021	integral to membrane
GO:0005886	plasma membrane

Molecular Function

GO:0042895	antibiotic transporter activity
GO:0005524	ATP binding
GO:0015226	carnitine transporter activity
GO:0015238	drug transporter activity
GO:0030165	PDZ domain binding
GO:0005515	protein binding
GO:0015651	quaternary ammonium group transmembrane transporter activity
GO:0015293	symporter activity

solute carrier family 22 (organic cation/carnitine transporter), member 5

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function