SON DNA binding protein

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Synonym

SON protein, Bax antagonist selected in saccharomyces 1, NREBP, C21orf50, Negative regulatory element-binding protein, DBP-5, FLJ21099, FLJ33914, SON3, NRE-binding protein, DBP5, BASS1, KIAA1019, SON DNA binding protein, SON

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:123.30 cerebellum:138.50 brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:245.40 spine:- retina:237.30 eye:170.40 artery/aorta:209.80 vein:- lymphnode:293.20 peripheral blood:255.10 spleen:37.80 thymus:154.60 bone marrow:334.60 adipose:80.70 bone:153.50 skin:182.40
GeneChip cerebrum:8.39 cerebellum:8.76 brain stem:8.43 corpus callosum/glia:8.74 pineal gland:- peripheral nerve:8.78 spine:8.63 retina:- eye:- artery/aorta:8.77 vein:8.25 lymphnode:9.18 peripheral blood:- spleen:9.39 thymus:9.93 bone marrow:8.70 adipose:8.67 bone:- skin:8.80
CAGE cerebrum:5.28 cerebellum:- brain stem:5.41 corpus callosum/glia:5.41 pineal gland:5.88 peripheral nerve:- spine:5.64 retina:- eye:- artery/aorta:5.03 vein:5.07 lymphnode:5.04 peripheral blood:- spleen:5.39 thymus:5.56 bone marrow:- adipose:5.29 bone:- skin:-
RNA-seq cerebrum:4.45 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.65 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.55 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:191.40 placenta:145.70 prostate:123.90 ovary:111.80 testis:121.10 heart:281 muscle:200.90 esophagus:- stomach:63.70 intestine:- colon:84.80     liver/hepato:728.30        lung:176    bladder:125.60 kidney:83.20 pituitary:811.90 thyroid/parathyroid:327.50 adrenal gland:- pancreas:88.90 breast:334.50 salivary:-
GeneChip uterus:9.26 placenta:8.89 prostate:9.54 ovary:9.28 testis:8.86 heart:8.34 muscle:8.41 esophagus:8.41 stomach:8.85 intestine:8.51 colon:7.81 liver/hepato:8.41 lung:9.05 bladder:- kidney:8.35 pituitary:9.20 thyroid/parathyroid:9.05 adrenal gland:8.88 pancreas:7.80 breast:8.92 salivary:8.59
CAGE uterus:5.54 placenta:5.33 prostate:5.22 ovary:5.44 testis:5.18 heart:5.13 muscle:5.61 esophagus:5.07 stomach:- intestine:5.20 colon:4.74     liver/hepato:4.90    lung:5.08 bladder:5.33 kidney:5.06 pituitary:5.78 thyroid/parathyroid:4.99 adrenal gland:- pancreas:4.75 breast:4.66 salivary:5.34
RNA-seq uterus:- placenta:- prostate:4.65 ovary:5.31 testis:4.77 heart:3.93 muscle:4.42 esophagus:- stomach:- intestine:- colon:4.49     liver/hepato:3.54        lung:4.32    bladder:- kidney:4.34 pituitary:- thyroid/parathyroid:5.03 adrenal gland:4.60 pancreas:- breast:4.40 salivary:-

Gene Information

IDs

Refseq ID NM_138927
Gene ID 6651
Unigene ID Hs.517262
Probe set ID 214988_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000159140
GTEx ID ENSG00000159140

Orthologous Gene

Mouse[16]  NM_019973, NM_178880
Rat [0]  

Chromosomal Region

21q22.11  [34,914,924  -  34,949,812]

Gene Family (Interpro ID)

IPR001159  Double-stranded RNA binding
IPR014720  Double-stranded RNA-binding-like

Link to Pubmed  (Pubmed ID)

1424986
1435773
1435774
1944255
3054499
8031013
8318737
10470851
10509013
10830953
10950926
11306577
11707072
11782456
12477932
14637006
14702039
14759258
15231748
15302935
15324660
16110330
16565220
16916647
16964243
17081983
17353931
17568003
18029348
18952841
19471022
19596686
20053686
20081832
20581448
21139048
21504830
21551269
21890473
21963094
22193954
22234250
22354994
22505724
22586326
22939629
23000965
23084401
23227827
23322776
23383273
23602568
23752268
24013217
24457600
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0000910  cytokinesis
GO:0000226  microtubule cytoskeleton organization
GO:0006397  mRNA processing
GO:0043066  negative regulation of apoptosis
GO:0051726  regulation of cell cycle
GO:0043484  regulation of RNA splicing
GO:0008380  RNA splicing

Cellular Component

GO:0016607  nuclear speck
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0003676  nucleic acid binding
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0050733  RS domain binding