sortilin-related receptor, L(DLR class) A repeats-containing

Synonym

LR11, LRP9, SorLA, SORL1, SORLA, Sortilin-related receptor precursor, SorLA-1, gp250, LDLR relative with 11 ligand-binding repeats

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:165.90

cerebellum:201.50

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:153.40

spine:112.30

retina:355.90

eye:117.50

artery/aorta:-

vein:-

lymphnode:343.80

peripheral blood:109.30

spleen:113.40

thymus:128.80

bone marrow:669.10

adipose:40.30

bone:25.60

skin:57.60

GeneChip

cerebrum:9.29

cerebellum:9.38

brain stem:9.59

corpus callosum/glia:9.70

pineal gland:-

peripheral nerve:7.66

spine:9.89

retina:-

eye:-

artery/aorta:6.54

vein:5.53

lymphnode:8.13

peripheral blood:-

spleen:7.94

thymus:8.01

bone marrow:8.66

adipose:5.45

bone:-

skin:6.57

CAGE

cerebrum:5.15

cerebellum:-

brain stem:5.27

corpus callosum/glia:5.55

pineal gland:5.33

peripheral nerve:-

spine:5.33

retina:-

eye:-

artery/aorta:3.67

vein:4.10

lymphnode:4.54

peripheral blood:-

spleen:4.09

thymus:4.24

bone marrow:-

adipose:2.03

bone:-

skin:-

RNA-seq

cerebrum:4.74

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.98

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.89

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:14.60

prostate:78.90

ovary:111.80

testis:69.20

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:76.30

liver/hepato:73.90

lung:88

bladder:-

kidney:62.40

pituitary:347.90

thyroid/parathyroid:-

adrenal gland:-

pancreas:160

breast:130.10

salivary:-

GeneChip

uterus:6.73

placenta:4.64

prostate:9.16

ovary:8.13

testis:6.41

heart:5.09

muscle:3.90

esophagus:6

stomach:6.59

intestine:6.39

colon:6.69

liver/hepato:9.24

lung:7.03

bladder:-

kidney:8.58

pituitary:8.96

thyroid/parathyroid:8.20

adrenal gland:5.63

pancreas:6.29

breast:6.88

salivary:8.31

CAGE

uterus:3.65

placenta:2.21

prostate:4.27

ovary:3.64

testis:3.47

heart:2.69

muscle:0.94

esophagus:3.14

stomach:-

intestine:4.00

colon:4.07

liver/hepato:4.67

lung:3.82

bladder:3.67

kidney:3.81

pituitary:4.81

thyroid/parathyroid:3.37

adrenal gland:-

pancreas:3.59

breast:2.95

salivary:4.73

RNA-seq

uterus:-

placenta:-

prostate:3.95

ovary:2.94

testis:3.06

heart:0.78

muscle:0.40

esophagus:-

stomach:-

intestine:-

colon:1.84

liver/hepato:2.79

lung:2.88

bladder:-

kidney:3.88

pituitary:-

thyroid/parathyroid:2.98

adrenal gland:2.20

pancreas:-

breast:1.83

salivary:-

IDs

Refseq ID	NM_003105
Gene ID	6653
Unigene ID	Hs.368592
Probe set ID	212560_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000137642
GTEx ID	ENSG00000137642

Orthologous Gene

Mouse[2]	NM_011436
Rat[2]	NM_011436

Chromosomal Region

11q24.1 [121,322,912 - 121,504,387]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold

Gene Ontology (GO ID)

Biological Process

GO:0008203	cholesterol metabolic process
GO:0006869	lipid transport
GO:0006898	receptor-mediated endocytosis

Cellular Component

GO:0005887	integral to plasma membrane
GO:0034362	low-density lipoprotein particle

Molecular Function

GO:0030169	low-density lipoprotein binding
GO:0004888	transmembrane receptor activity

sortilin-related receptor, L(DLR class) A repeats-containing

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function