son of sevenless homolog 1 (Drosophila)

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Synonym

hereditary, Son of sevenless homolog 1, GGF1, SOS1, son of sevenless homolog 1 (Drosophila), SOS-1, GINGF, GF1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:4.87

cerebellum:4.39

brain stem:4.91

corpus callosum/glia:4.81

pineal gland:-

peripheral nerve:6.54

spine:4.89

retina:-

eye:-

artery/aorta:5.52

vein:5.48

lymphnode:5.68

peripheral blood:-

spleen:5.50

thymus:5.52

bone marrow:5.21

adipose:6.20

bone:-

skin:5.80

CAGE

cerebrum:3.74

cerebellum:-

brain stem:3.83

corpus callosum/glia:3.43

pineal gland:3.84

peripheral nerve:-

spine:3.74

retina:-

eye:-

artery/aorta:3.83

vein:3.71

lymphnode:3.60

peripheral blood:-

spleen:3.52

thymus:3.84

bone marrow:-

adipose:4.07

bone:-

skin:-

RNA-seq

cerebrum:2.51

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.43

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.22

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:5.35

placenta:5.59

prostate:5.94

ovary:5.25

testis:6.07

heart:5.13

muscle:5.34

esophagus:5.41

stomach:5.15

intestine:5.21

colon:4.76

liver/hepato:5.06

lung:5.44

bladder:-

kidney:5.06

pituitary:5.24

thyroid/parathyroid:5.41

adrenal gland:5.15

pancreas:4.42

breast:5.67

salivary:4.68

CAGE

uterus:3.95

placenta:3.61

prostate:3.96

ovary:3.87

testis:3.63

heart:3.68

muscle:3.62

esophagus:3.77

stomach:-

intestine:4.02

colon:3.83

liver/hepato:3.08

lung:3.99

bladder:3.98

kidney:3.31

pituitary:3.88

thyroid/parathyroid:3.48

adrenal gland:-

pancreas:2.81

breast:4.25

salivary:3.30

RNA-seq

uterus:-

placenta:-

prostate:3.71

ovary:4.05

testis:3.40

heart:2.83

muscle:3.13

esophagus:-

stomach:-

intestine:-

colon:3.15

liver/hepato:1.92

lung:2.85

bladder:-

kidney:2.98

pituitary:-

thyroid/parathyroid:3.03

adrenal gland:2.74

pancreas:-

breast:4.22

salivary:-

IDs

Refseq ID	NM_005633
Gene ID	6654
Unigene ID	-
Probe set ID	212780_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000115904
GTEx ID	ENSG00000115904

Orthologous Gene

Mouse[6]	NM_009231
Rat[2]	NM_001100716

Chromosomal Region

2p22.1 [39,208,537 - 39,351,486]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001849

Pleckstrin homology

Gene Ontology (GO ID)

Biological Process

GO:0007411	axon guidance
GO:0007596	blood coagulation
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0045087	innate immune response
GO:0008286	insulin receptor signaling pathway
GO:0050900	leukocyte migration
GO:0048011	nerve growth factor receptor signaling pathway
GO:0030168	platelet activation
GO:0043065	positive regulation of apoptosis
GO:0032321	positive regulation of Rho GTPase activity
GO:0007265	Ras protein signal transduction
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction

Cellular Component

GO:0005829	cytosol
GO:0005886	plasma membrane

Molecular Function

GO:0003677	DNA binding
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0005088	Ras guanyl-nucleotide exchange factor activity
GO:0005100	Rho GTPase activator activity
GO:0005089	Rho guanyl-nucleotide exchange factor activity

son of sevenless homolog 1 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function