SRY (sex determining region Y)-box 4

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Synonym

SRY (sex determining region Y)-box 4, EVI16, SOX4, Transcription factor SOX-4

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.88 cerebellum:6.21 brain stem:4.48 corpus callosum/glia:5.16 pineal gland:- peripheral nerve:6.62 spine:5.36 retina:- eye:- artery/aorta:6.48 vein:6.64 lymphnode:6.17 peripheral blood:- spleen:6.80 thymus:10.02 bone marrow:6.47 adipose:7.01 bone:- skin:6.99
CAGE cerebrum:2.57 cerebellum:- brain stem:2.19 corpus callosum/glia:2.70 pineal gland:3.26 peripheral nerve:- spine:2.63 retina:- eye:- artery/aorta:4.11 vein:4.23 lymphnode:3.10 peripheral blood:- spleen:2.89 thymus:5.93 bone marrow:- adipose:4.00 bone:- skin:-
RNA-seq cerebrum:1.02 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.03 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.28 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:9.35 placenta:6.76 prostate:8.23 ovary:9.04 testis:7.46 heart:6.75 muscle:4.85 esophagus:5.90 stomach:7.45 intestine:7.78 colon:7.84 liver/hepato:4.42 lung:7.63 bladder:- kidney:7.20 pituitary:6.48 thyroid/parathyroid:7.50 adrenal gland:5.50 pancreas:7.03 breast:8.31 salivary:6.79
CAGE uterus:4.73 placenta:3.46 prostate:4.11 ovary:4.27 testis:4.28 heart:3.42 muscle:2.56 esophagus:2.98 stomach:- intestine:3.32 colon:3.62     liver/hepato:2.38    lung:4.01 bladder:3.58 kidney:3.76 pituitary:2.50 thyroid/parathyroid:3.49 adrenal gland:- pancreas:3.95 breast:4.62 salivary:3.73
RNA-seq uterus:- placenta:- prostate:3.64 ovary:4.87 testis:4.51 heart:1.19 muscle:1.43 esophagus:- stomach:- intestine:- colon:3.26     liver/hepato:0.70        lung:4.73    bladder:- kidney:3.19 pituitary:- thyroid/parathyroid:3.47 adrenal gland:2.39 pancreas:- breast:4.22 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0003289  atrial septum primum morphogenesis
GO:0003215  cardiac right ventricle morphogenesis
GO:0003211  cardiac ventricle formation
GO:0071333  cellular response to glucose stimulus
GO:0042769  DNA damage response, detection of DNA damage
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0031018  endocrine pancreas development
GO:0021782  glial cell development
GO:0014009  glial cell proliferation
GO:0042593  glucose homeostasis
GO:0007507  heart development
GO:0060174  limb bud formation
GO:0003183  mitral valve morphogenesis
GO:0060548  negative regulation of cell death
GO:0008285  negative regulation of cell proliferation
GO:0046826  negative regulation of protein export from nucleus
GO:0031397  negative regulation of protein ubiquitination
GO:0001841  neural tube formation
GO:0060563  neuroepithelial cell differentiation
GO:0003357  noradrenergic neuron differentiation
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0032024  positive regulation of insulin secretion
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0045727  positive regulation of translation
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0002328  pro-B cell differentiation
GO:0050821  protein stabilization
GO:0031647  regulation of protein stability
GO:0006355  regulation of transcription, DNA-dependent
GO:0001501  skeletal system development
GO:0035019  somatic stem cell maintenance
GO:0021510  spinal cord development
GO:0021522  spinal cord motor neuron differentiation
GO:0048485  sympathetic nervous system development
GO:0030217  T cell differentiation
GO:0060412  ventricular septum morphogenesis
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0003700  transcription factor activity