SRY (sex determining region Y)-box 10

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Synonym

SRY (sex determining region Y)-box 10, SOX10, DOM, MGC15649, WS4, Transcription factor SOX-10

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:19

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:245.40

spine:224.60

retina:-

eye:70.50

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:19.20

GeneChip

cerebrum:7.14

cerebellum:6.48

brain stem:7.28

corpus callosum/glia:7.90

pineal gland:-

peripheral nerve:7.47

spine:7.32

retina:-

eye:-

artery/aorta:6.25

vein:6.39

lymphnode:6.30

peripheral blood:-

spleen:6.02

thymus:6.03

bone marrow:6.54

adipose:6.46

bone:-

skin:6.35

CAGE

cerebrum:4.56

cerebellum:-

brain stem:5.55

corpus callosum/glia:6.25

pineal gland:2.89

peripheral nerve:-

spine:4.88

retina:-

eye:-

artery/aorta:2.28

vein:2.40

lymphnode:1.04

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:1.57

bone:-

skin:-

RNA-seq

cerebrum:4.42

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.91

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.17

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:24.40

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:55.80

salivary:-

GeneChip

uterus:6.04

placenta:6.07

prostate:5.92

ovary:6.02

testis:6.05

heart:6.58

muscle:6.65

esophagus:6.35

stomach:6.40

intestine:6.42

colon:6.89

liver/hepato:6.36

lung:6.07

bladder:-

kidney:6.40

pituitary:6.38

thyroid/parathyroid:5.96

adrenal gland:6.43

pancreas:6.44

breast:6.58

salivary:8.05

CAGE

uterus:2.28

placenta:0

prostate:2.46

ovary:1.92

testis:1.75

heart:2.13

muscle:0.65

esophagus:3.02

stomach:-

intestine:2.03

colon:2.56

liver/hepato:0.36

lung:0.51

bladder:2.77

kidney:0.27

pituitary:1.24

thyroid/parathyroid:1.02

adrenal gland:-

pancreas:0

breast:3.16

salivary:5.31

RNA-seq

uterus:-

placenta:-

prostate:2.14

ovary:0.75

testis:1.63

heart:0.60

muscle:0.37

esophagus:-

stomach:-

intestine:-

colon:2.63

liver/hepato:0.10

lung:0.47

bladder:-

kidney:0.15

pituitary:-

thyroid/parathyroid:0.42

adrenal gland:0.51

pancreas:-

breast:2.98

salivary:-

IDs

Refseq ID	NM_006941
Gene ID	6663
Unigene ID	Hs.376984
Probe set ID	209843_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000100146
GTEx ID	ENSG00000100146

Orthologous Gene

Mouse[3]	NM_011437
Rat [0]

Chromosomal Region

22q13.1 [38,366,693 - 38,383,429]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000910	High mobility group, HMG1/HMG2
IPR009071	High mobility group, superfamily

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0048469	cell maturation
GO:0048589	developmental growth
GO:0048546	digestive tract morphogenesis
GO:0048484	enteric nervous system development
GO:0001701	in utero embryonic development
GO:0030318	melanocyte differentiation
GO:0043066	negative regulation of apoptosis
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001755	neural crest cell migration
GO:0048709	oligodendrocyte differentiation
GO:0007422	peripheral nervous system development
GO:0014015	positive regulation of gliogenesis
GO:0002052	positive regulation of neuroblast proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006357	regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0031315	extrinsic to mitochondrial outer membrane
GO:0005634	nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0003713	transcription coactivator activity
GO:0008134	transcription factor binding

SRY (sex determining region Y)-box 10

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function