Sp2 transcription factor

 jump to detail

Synonym

Transcription factor Sp2, Sp2 transcription factor, SP2, KIAA0048

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:237.30 eye:41.10 artery/aorta:- vein:133.30 lymphnode:80.90 peripheral blood:18.20 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:28.80
GeneChip cerebrum:6.09 cerebellum:6.29 brain stem:6.05 corpus callosum/glia:6.37 pineal gland:- peripheral nerve:6.38 spine:6.57 retina:- eye:- artery/aorta:6.28 vein:5.98 lymphnode:6.64 peripheral blood:- spleen:7 thymus:7.57 bone marrow:6.84 adipose:6.31 bone:- skin:6.42
CAGE cerebrum:2.98 cerebellum:- brain stem:2.84 corpus callosum/glia:3.42 pineal gland:3.12 peripheral nerve:- spine:2.92 retina:- eye:- artery/aorta:3.22 vein:3.18 lymphnode:3.31 peripheral blood:- spleen:3.13 thymus:3.42 bone marrow:- adipose:2.75 bone:- skin:-
RNA-seq cerebrum:2.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.99 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.91 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:18.20 prostate:90.10 ovary:37.30 testis:121.10 heart:63.90 muscle:20.10 esophagus:- stomach:- intestine:- colon:17     liver/hepato:21.10        lung:19.60    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:37.20 salivary:-
GeneChip uterus:6.37 placenta:6.95 prostate:6.78 ovary:6.27 testis:6.38 heart:6.04 muscle:7.04 esophagus:6.36 stomach:6.34 intestine:6.51 colon:6.56 liver/hepato:5.77 lung:6.22 bladder:- kidney:6.54 pituitary:5.97 thyroid/parathyroid:6.79 adrenal gland:6.25 pancreas:5.47 breast:6.82 salivary:6.68
CAGE uterus:3.12 placenta:3.11 prostate:2.98 ovary:3.06 testis:3.32 heart:2.76 muscle:3.13 esophagus:3.01 stomach:- intestine:3.15 colon:2.82     liver/hepato:2.60    lung:2.81 bladder:2.77 kidney:2.88 pituitary:2.75 thyroid/parathyroid:2.97 adrenal gland:- pancreas:2.98 breast:2.87 salivary:2.93
RNA-seq uterus:- placenta:- prostate:3.10 ovary:3.01 testis:3.03 heart:2.37 muscle:3.15 esophagus:- stomach:- intestine:- colon:2.46     liver/hepato:1.61        lung:2.89    bladder:- kidney:2.35 pituitary:- thyroid/parathyroid:3.58 adrenal gland:3.50 pancreas:- breast:2.76 salivary:-

Gene Information

IDs

Refseq ID NM_003110
Gene ID 6668
Unigene ID Hs.514276
Probe set ID 204367_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000167182
GTEx ID ENSG00000167182

Orthologous Gene

Mouse[2]  NM_001080964, NM_030220
Rat[1]  NM_001107045, NM_030220

Chromosomal Region

17q21.32  [45,973,516  -  46,006,323]

Gene Family (Interpro ID)

IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

1341900
7584044
9730617
10454592
10547281
12477932
14702039
14726517
15126343
15489334
15788387
15953604
15987735
16201967
16467376
17071613
17827154
18029348
18051367
19482358
19698806
19834535
21832049
23667531
24163370

Gene Ontology  (GO ID)

Biological Process

GO:0048568  embryonic organ development
GO:0048144  fibroblast proliferation
GO:0006955  immune response
GO:0001701  in utero embryonic development
GO:0035264  multicellular organism growth
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0042826  histone deacetylase binding
GO:0046872  metal ion binding