dystonin

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8 cerebellum:7.23 brain stem:8.49 corpus callosum/glia:8.58 pineal gland:- peripheral nerve:8.11 spine:8.17 retina:- eye:- artery/aorta:7.35 vein:7.47 lymphnode:6.16 peripheral blood:- spleen:6.29 thymus:6 bone marrow:5.87 adipose:7.04 bone:- skin:6.57
CAGE cerebrum:1.65 cerebellum:- brain stem:1.87 corpus callosum/glia:0.29 pineal gland:1.70 peripheral nerve:- spine:1.70 retina:- eye:- artery/aorta:0.47 vein:0.59 lymphnode:0.26 peripheral blood:- spleen:0.17 thymus:0.28 bone marrow:- adipose:0.78 bone:- skin:-
RNA-seq cerebrum:4.84 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.69 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.12 placenta:6.84 prostate:6.86 ovary:7.24 testis:6.78 heart:7.54 muscle:7.70 esophagus:6.81 stomach:6.86 intestine:7.10 colon:6.94 liver/hepato:6.95 lung:7.38 bladder:- kidney:6.68 pituitary:7.02 thyroid/parathyroid:5.88 adrenal gland:6.96 pancreas:6.30 breast:6.67 salivary:6.79
CAGE uterus:0.57 placenta:0.43 prostate:0.97 ovary:0.60 testis:0.31 heart:1.79 muscle:1.21 esophagus:1.88 stomach:- intestine:0.48 colon:0.56     liver/hepato:0.71    lung:1.40 bladder:1.84 kidney:0.39 pituitary:1.80 thyroid/parathyroid:0.17 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:3.99 ovary:3.78 testis:3.61 heart:4.80 muscle:4.03 esophagus:- stomach:- intestine:- colon:4.18     liver/hepato:2.15        lung:4.36    bladder:- kidney:2.89 pituitary:- thyroid/parathyroid:3.38 adrenal gland:2.96 pancreas:- breast:3.59 salivary:-

Gene Information

IDs

Refseq ID NM_015548
Gene ID 667
Unigene ID -
Probe set ID 212253_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000151914
GTEx ID ENSG00000151914

Orthologous Gene

Mouse[4]  NM_133833, NM_134448
Rat[4]  NM_133833, NM_134448

Chromosomal Region

6p12.1  [56,322,785  -  56,819,426]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR016146  Calponin-homology
IPR001715  Calponin-like actin-binding
IPR018249  EF-HAND 2
IPR018159  Spectrin/alpha-actinin

Link to Pubmed  (Pubmed ID)

1712022
1717441
2045679
2090522
2276744
2461961
2579167
2645368
3880796
7818282
7919656
8010969
8345227
8349819
8575775
8621649
8889548
8889549
9872452
10428034
10637308
10727295
10811835
11323216
11375975
11751855
12168954
12421765
12477932
12482924
12542537
12802069
14574404
14576348
14581450
14668477
14702039
14705806
15231748
15342556
15489334
15560761
15725571
15840729
16344560
16512878
16757171
17043677
17081983
17161423
17920818
18029348
18207369
19403692
19596686
19616115
19632184
19932097
20164846
20379614
20479946
20682791
20800603
20811636
20936779
21139048
21638337
21642434
22337587
22522446
22558309
22586326
22678362
22939629
22995871
23000965
23269794
23455922
23903849
24025550
24250222
24255178
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0007155  cell adhesion
GO:0007050  cell cycle arrest
GO:0048870  cell motility
GO:0031122  cytoplasmic microtubule organization
GO:0007010  cytoskeleton organization
GO:0030198  extracellular matrix organization
GO:0031581  hemidesmosome assembly
GO:0007229  integrin-mediated signaling pathway
GO:0045104  intermediate filament cytoskeleton organization
GO:0030011  maintenance of cell polarity
GO:0000226  microtubule cytoskeleton organization
GO:0031110  regulation of microtubule polymerization or depolymerization
GO:0009611  response to wounding
GO:0008090  retrograde axon cargo transport

Cellular Component

GO:0015629  actin cytoskeleton
GO:0030424  axon
GO:0033267  axon part
GO:0009925  basal plasma membrane
GO:0005604  basement membrane
GO:0005938  cell cortex
GO:0031252  cell leading edge
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005829  cytosol
GO:0005789  endoplasmic reticulum membrane
GO:0031673  H zone
GO:0030056  hemidesmosome
GO:0016021  integral to membrane
GO:0005882  intermediate filament
GO:0045111  intermediate filament cytoskeleton
GO:0015630  microtubule cytoskeleton
GO:0060053  neurofilament cytoskeleton
GO:0005635  nuclear envelope
GO:0005634  nucleus
GO:0030018  Z disc

Molecular Function

GO:0003779  actin binding
GO:0005509  calcium ion binding
GO:0005178  integrin binding
GO:0051010  microtubule plus-end binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0042803  protein homodimerization activity