serine peptidase inhibitor, Kazal type 1

Synonym

Spink3, SPINK1, serine peptidase inhibitor, Kazal type 1, PCTT, Tumor-associated trypsin inhibitor, PSTI, Pancreatic secretory trypsin inhibitor precursor, TATI, Serine protease inhibitor Kazal-type 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:3.73

cerebellum:3.78

brain stem:3.74

corpus callosum/glia:3.65

pineal gland:-

peripheral nerve:3.66

spine:3.69

retina:-

eye:-

artery/aorta:4.83

vein:3.78

lymphnode:3.82

peripheral blood:-

spleen:4

thymus:3.75

bone marrow:3.91

adipose:3.87

bone:-

skin:4.12

CAGE

cerebrum:0.01

cerebellum:-

brain stem:0

corpus callosum/glia:0.39

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:1.79

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.93

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:64.80

colon:93.30

liver/hepato:42.20

lung:-

bladder:628.10

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:329

breast:-

salivary:-

GeneChip

uterus:3.79

placenta:4.12

prostate:3.93

ovary:3.83

testis:3.77

heart:3.58

muscle:3.73

esophagus:3.68

stomach:9.88

intestine:10.18

colon:8.79

liver/hepato:4.04

lung:3.89

bladder:-

kidney:5.46

pituitary:3.91

thyroid/parathyroid:3.93

adrenal gland:3.68

pancreas:13.04

breast:3.99

salivary:4.14

CAGE

uterus:0.27

placenta:0

prostate:3.52

ovary:0

testis:0.83

heart:0.09

muscle:0

esophagus:0

stomach:-

intestine:5.22

colon:4.94

liver/hepato:5.62

lung:0.40

bladder:4.09

kidney:3.35

pituitary:0

thyroid/parathyroid:0.12

adrenal gland:-

pancreas:10.75

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:8.12

ovary:0

testis:0.27

heart:0.23

muscle:0

esophagus:-

stomach:-

intestine:-

colon:6.33

liver/hepato:11.10

lung:0.04

bladder:-

kidney:6.91

pituitary:-

thyroid/parathyroid:0.67

adrenal gland:0

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_003122
Gene ID	6690
Unigene ID	Hs.407856
Probe set ID	206239_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000164266
GTEx ID	ENSG00000164266

Orthologous Gene

Mouse[1]	NM_009258
Rat [0]

Chromosomal Region

5q32 [147,204,131 - 147,211,349]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002350	Proteinase inhibitor I1, Kazal
IPR001239	Proteinase inhibitor I1, Kazal metazoa

Gene Ontology (GO ID)

Biological Process

GO:0010751	negative regulation of nitric oxide mediated signal transduction
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
GO:0060046	regulation of acrosome reaction

Cellular Component

GO:0005576

extracellular region

Molecular Function

GO:0004866	endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0004867	serine-type endopeptidase inhibitor activity

serine peptidase inhibitor, Kazal type 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function