SH3 and cysteine rich domain

 jump to detail

Synonym

STAC1, SH3 and cysteine-rich domain-containing protein, STAC, SH3 and cysteine rich domain, SRC homology 3 and cysteine-rich domain protein, FLJ32331

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.90 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:- peripheral blood:54.70 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:19.20
GeneChip cerebrum:6.15 cerebellum:6.53 brain stem:6.35 corpus callosum/glia:6.13 pineal gland:- peripheral nerve:8.73 spine:6.19 retina:- eye:- artery/aorta:6.45 vein:6.42 lymphnode:5.86 peripheral blood:- spleen:5.94 thymus:5.65 bone marrow:6.17 adipose:6.12 bone:- skin:5.95
CAGE cerebrum:0.90 cerebellum:- brain stem:0.93 corpus callosum/glia:0.85 pineal gland:2.87 peripheral nerve:- spine:0.93 retina:- eye:- artery/aorta:3.01 vein:0.70 lymphnode:0.46 peripheral blood:- spleen:0.25 thymus:0.50 bone marrow:- adipose:1.37 bone:- skin:-
RNA-seq cerebrum:0.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.09 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.45 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:10.90 prostate:45.10 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:19.60    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:27.90 salivary:-
GeneChip uterus:6.05 placenta:6.08 prostate:6.28 ovary:6.19 testis:5.91 heart:6.26 muscle:6.38 esophagus:6.09 stomach:6.11 intestine:6.08 colon:6.35 liver/hepato:6.30 lung:6.94 bladder:- kidney:6.40 pituitary:6.14 thyroid/parathyroid:5.70 adrenal gland:6.17 pancreas:6.39 breast:5.87 salivary:6.25
CAGE uterus:2.16 placenta:0.30 prostate:2.58 ovary:0.86 testis:1.20 heart:0.70 muscle:1.44 esophagus:1.44 stomach:- intestine:0.43 colon:0.87     liver/hepato:0.96    lung:2.61 bladder:2.16 kidney:1.24 pituitary:0.76 thyroid/parathyroid:0.76 adrenal gland:- pancreas:0.58 breast:1.92 salivary:1.15
RNA-seq uterus:- placenta:- prostate:2.83 ovary:0.64 testis:1.52 heart:0.13 muscle:0.50 esophagus:- stomach:- intestine:- colon:2.19     liver/hepato:0.09        lung:2.23    bladder:- kidney:1.22 pituitary:- thyroid/parathyroid:1.20 adrenal gland:0.56 pancreas:- breast:0.53 salivary:-

Gene Information

IDs

Refseq ID NM_003149
Gene ID 6769
Unigene ID Hs.56045
Probe set ID 205743_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000144681
GTEx ID ENSG00000144681

Orthologous Gene

Mouse[1]  NM_016853
Rat[1]  NM_016853

Chromosomal Region

3p22.3  [36,421,836  -  36,589,499]

Gene Family (Interpro ID)

IPR013315  Spectrin alpha chain, SH3 domain
IPR020473  Src homology-3, region

Link to Pubmed  (Pubmed ID)

8954993
10393425
12477932
14702039
16260042
18654987
19953087
21832049
22704111
23936387
23940030

Gene Ontology  (GO ID)

Biological Process

GO:0034605  cellular response to heat
GO:0007165  signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0046872  metal ion binding