steroidogenic acute regulatory protein

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Synonym

STAR, steroidogenic acute regulatory protein, steroidogenic acute regulator, StARD1, StAR, STARD1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:115 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.06 cerebellum:4.73 brain stem:5.28 corpus callosum/glia:4.47 pineal gland:- peripheral nerve:4.50 spine:4.69 retina:- eye:- artery/aorta:4.33 vein:4.52 lymphnode:5.89 peripheral blood:- spleen:4.26 thymus:4.74 bone marrow:4.66 adipose:4.45 bone:- skin:4.74
CAGE cerebrum:0.81 cerebellum:- brain stem:0.84 corpus callosum/glia:3.57 pineal gland:0 peripheral nerve:- spine:0.54 retina:- eye:- artery/aorta:0.47 vein:0.18 lymphnode:0.34 peripheral blood:- spleen:0.17 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:1.25 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.23 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.15 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:14.60 prostate:11.30 ovary:260.80 testis:289.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:19.60    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:17724.70 pancreas:- breast:- salivary:-
GeneChip uterus:4.38 placenta:4.21 prostate:4.17 ovary:7.30 testis:8.47 heart:4.59 muscle:4.58 esophagus:4.72 stomach:4.31 intestine:4.49 colon:4.46 liver/hepato:4.55 lung:4.31 bladder:- kidney:4.42 pituitary:4.89 thyroid/parathyroid:4.46 adrenal gland:13.28 pancreas:4.78 breast:4.49 salivary:4.57
CAGE uterus:0.20 placenta:0.16 prostate:0 ovary:5.90 testis:4.36 heart:0.17 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0.96 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.25 ovary:7.67 testis:4.44 heart:0.03 muscle:0.06 esophagus:- stomach:- intestine:- colon:0.11     liver/hepato:0.06        lung:0.13    bladder:- kidney:0.20 pituitary:- thyroid/parathyroid:0.10 adrenal gland:0.51 pancreas:- breast:0.34 salivary:-

Gene Information

IDs

Refseq ID NM_000349
Gene ID 6770
Unigene ID Hs.521535
Probe set ID 204548_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000147465
GTEx ID ENSG00000147465

Orthologous Gene

Mouse[3]  NM_011485
Rat [0]  

Chromosomal Region

8p11.23  [38,001,167  -  38,008,783]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7547998
7548191
7761400
8619474
8634702
8943003
8948562
9097960
9110174
9188726
9398748
9804848
10323391
10548884
10566637
10802740
11061515
11145563
11489878
12044915
12372832
12477932
12530644
12727988
12834921
12843197
12909641
12925534
12933667
14565954
14702039
14726488
14764819
15181096
15489334
15546900
15583024
15666812
15777208
15897605
15985476
16162390
16169070
16234239
16901925
16973755
16990645
17374711
17433772
17666473
18000307
18084157
18191841
18250166
18331352
18341481
18450961
18490834
18505908
18583320
18636124
18665078
18729825
18829024
18945429
19001523
19022561
19095060
19231010
19271249
19272380
19453261
19744555
19849856
19899816
19903795
19913121
19930843
19946756
20199803
20379614
20444910
20601698
20628086
20660033
20734064
20877624
21145937
21147196
21164258
21217523
21334384
21350237
21647419
21846663
22213075
22253417
22634420
23029457
23158025
23211570
23330251
23748066
23825130
23920000
24053410
24124408

Gene Ontology  (GO ID)

Biological Process

GO:0006699  bile acid biosynthetic process
GO:0018879  biphenyl metabolic process
GO:0007420  brain development
GO:0006700  C21-steroid hormone biosynthetic process
GO:0071312  cellular response to alkaloid
GO:0071236  cellular response to antibiotic
GO:0071276  cellular response to cadmium ion
GO:0071320  cellular response to cAMP
GO:0071372  cellular response to follicle-stimulating hormone stimulus
GO:0071333  cellular response to glucose stimulus
GO:0071378  cellular response to growth hormone stimulus
GO:0032869  cellular response to insulin stimulus
GO:0071346  cellular response to interferon-gamma
GO:0071222  cellular response to lipopolysaccharide
GO:0071373  cellular response to luteinizing hormone stimulus
GO:0008203  cholesterol metabolic process
GO:0042747  circadian sleep/wake cycle, REM sleep
GO:0018894  dibenzo-p-dioxin metabolic process
GO:0016101  diterpenoid metabolic process
GO:0006703  estrogen biosynthetic process
GO:0050756  fractalkine metabolic process
GO:0008211  glucocorticoid metabolic process
GO:0017143  insecticide metabolic process
GO:0032367  intracellular cholesterol transport
GO:0008584  male gonad development
GO:0018958  phenol metabolic process
GO:0018963  phthalate metabolic process
GO:0010628  positive regulation of gene expression
GO:0050769  positive regulation of neurogenesis
GO:0006701  progesterone biosynthetic process
GO:0048168  regulation of neuronal synaptic plasticity
GO:0050810  regulation of steroid biosynthetic process
GO:0051412  response to corticosterone stimulus
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0045471  response to ethanol
GO:0009635  response to herbicide
GO:0042542  response to hydrogen peroxide
GO:0010212  response to ionizing radiation
GO:0010288  response to lead ion
GO:0035094  response to nicotine
GO:0007584  response to nutrient
GO:0006694  steroid biosynthetic process
GO:0008202  steroid metabolic process

Cellular Component

GO:0043025  cell soma
GO:0005829  cytosol
GO:0030061  mitochondrial crista
GO:0005758  mitochondrial intermembrane space
GO:0043005  neuron projection

Molecular Function

GO:0015485  cholesterol binding
GO:0017127  cholesterol transporter activity