signal transducer and activator of transcription 5A

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Synonym

STAT 5A, Stat 5a, STAT 5a, STAT5A, STAT-5A, Stat-5A, STAT5a, STAT-5a, MGF, Stat-5a, STAT5, Stat 5A

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:58.80 artery/aorta:60 vein:- lymphnode:141.50 peripheral blood:109.30 spleen:75.60 thymus:206.10 bone marrow:19.70 adipose:40.30 bone:115.20 skin:28.80
GeneChip cerebrum:5.64 cerebellum:5.72 brain stem:5.61 corpus callosum/glia:5.91 pineal gland:- peripheral nerve:6.30 spine:6.06 retina:- eye:- artery/aorta:6.52 vein:6.54 lymphnode:7.02 peripheral blood:- spleen:6.62 thymus:6.64 bone marrow:6.74 adipose:7.07 bone:- skin:6.39
CAGE cerebrum:2.08 cerebellum:- brain stem:2.39 corpus callosum/glia:2.57 pineal gland:1.43 peripheral nerve:- spine:2.71 retina:- eye:- artery/aorta:3.12 vein:3.90 lymphnode:3.56 peripheral blood:- spleen:3.33 thymus:3.51 bone marrow:- adipose:4.41 bone:- skin:-
RNA-seq cerebrum:1.71 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.22 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.71 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:36.40 prostate:56.30 ovary:74.50 testis:4.30 heart:51.10 muscle:20.10 esophagus:- stomach:106.20 intestine:32.40 colon:50.90     liver/hepato:42.20        lung:53.80    bladder:125.60 kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:37.20 salivary:-
GeneChip uterus:6.14 placenta:6.56 prostate:6.03 ovary:6.54 testis:5.49 heart:6.09 muscle:6.08 esophagus:6.06 stomach:6.13 intestine:6.17 colon:6.46 liver/hepato:6.04 lung:6.50 bladder:- kidney:6.41 pituitary:6.12 thyroid/parathyroid:6.32 adrenal gland:6.45 pancreas:6.22 breast:6.78 salivary:6.16
CAGE uterus:3.16 placenta:2.96 prostate:3.30 ovary:3.37 testis:2.75 heart:3.10 muscle:3.11 esophagus:3.10 stomach:- intestine:2.46 colon:3.07     liver/hepato:2.28    lung:3.08 bladder:3.61 kidney:2.59 pituitary:2.08 thyroid/parathyroid:2.76 adrenal gland:- pancreas:2.71 breast:3.43 salivary:2.85
RNA-seq uterus:- placenta:- prostate:3.84 ovary:3.92 testis:3.20 heart:1.77 muscle:3.85 esophagus:- stomach:- intestine:- colon:3.60     liver/hepato:1.35        lung:3.76    bladder:- kidney:2.64 pituitary:- thyroid/parathyroid:3.42 adrenal gland:4.32 pancreas:- breast:5.12 salivary:-

IDs

Refseq ID NM_003152
Gene ID 6776
Unigene ID Hs.437058
Probe set ID 203010_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000126561
GTEx ID ENSG00000126561

Orthologous Gene

Mouse[4]  NM_001164062, NM_011488
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7719937
7719938
7925280
8617237
8631883
8702683
8732682
8878484
8977232
9030599
9047382
9122188
9373245
9398404
9484840
9528750
9575217
9657743
9773981
9837784
9880255
9989503
10037026
10037796
10194762
10358045
10358079
10374881
10428030
10570284
10594041
10602027
10617656
10652277
10825200
10996427
11030348
11097834
11158330
11167825
11413148
11418623
11418668
11440634
11485409
11682624
11722592
11726519
11756417
11779872
11861304
11867689
11923474
11973644
11997457
12039028
12039059
12060651
12091337
12193575
12198240
12208876
12237455
12377952
12393707
12456798
12459499
12477932
12574125
12605694
12847485
12901872
12954634
14597631
14637146
14645506
14696092
14704793
14726409
14726487
15010467
15048088
15063762
15128421
15169792
15304355
15313458
15353555
15358227
15489334
15534001
15588985
15592524
15611091
15644415
15652752
15677474
15735688
15795318
16115927
16133357
16189514
16289657
16303247
16407271
16455947
16476059
16502315
16532027
16572323
16684963
16729043
16804404
16819511
16840779
16954437
16973758
17015686
17038539
17081983
17128418
17169805
17214852
17220171
17330131
17332243
17376889
17387179
17438530
17639043
17666591
17703412
17726024
17846080
17867599
17913706
17922009
17938255
18023521
18029348
18063684
18172316
18250158
18270368
18271926
18296629
18378698
18413343
18436865
18460645
18483262
18616510
18660489
18779318
18830265
18838617
19036881
19258923
19262752
19276230
19309697
19362457
19423540
19423653
19491198
19571317
19675167
19779039
19797429
19817957
19864382
19923221
19956772
19966185
20065083
20113333
20124477
20196786
20214633
20233708
20331378
20339093
20388848
20406964
20415542
20438785
20489169
20503287
20508164
20530519
20716621
20849385
20952588
20974963
21079973
21220747
21233313
21263150
21464042
21531896
21542777
21602494
21606506
21619451
21698228
21704724
21749449
21763497
21771882
21785216
21816901
21826656
21890473
21900206
21963094
21988832
22046434
22053931
22065720
22159083
22196377
22367509
22505724
22584572
22753752
22781567
22926520
23111066
23128233
23134344
23151802
23161573
23223023
23243289
23262295
23332799
23406773
23438599
23458731
23465551
23533197
23593005
23621408
23660011
23716595
23729680
23733954
23773921
24040307
24068731
24135280
24155890
24263804
24335105
24384092
24394665
24523507

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0000255  allantoin metabolic process
GO:0006101  citrate metabolic process
GO:0006600  creatine metabolic process
GO:0046449  creatinine metabolic process
GO:0046543  development of secondary female sexual characteristics
GO:0046544  development of secondary male sexual characteristics
GO:0060742  epithelial cell differentiation involved in prostate gland development
GO:0006631  fatty acid metabolic process
GO:0007565  female pregnancy
GO:0006549  isoleucine metabolic process
GO:0007259  JAK-STAT cascade
GO:0060397  JAK-STAT cascade involved in growth hormone signaling pathway
GO:0007595  lactation
GO:0019915  lipid storage
GO:0001553  luteinization
GO:0001779  natural killer cell differentiation
GO:0045647  negative regulation of erythrocyte differentiation
GO:0033026  negative regulation of mast cell apoptosis
GO:0006107  oxaloacetate metabolic process
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048541  Peyer's patch development
GO:0042104  positive regulation of activated T cell proliferation
GO:0045579  positive regulation of B cell differentiation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0050729  positive regulation of inflammatory response
GO:0045086  positive regulation of interleukin-2 biosynthetic process
GO:0060376  positive regulation of mast cell differentiation
GO:0070668  positive regulation of mast cell proliferation
GO:0045931  positive regulation of mitotic cell cycle
GO:0040018  positive regulation of multicellular organism growth
GO:0032825  positive regulation of natural killer cell differentiation
GO:0045954  positive regulation of natural killer cell mediated cytotoxicity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060740  prostate gland epithelium morphogenesis
GO:0030155  regulation of cell adhesion
GO:0030856  regulation of epithelial cell differentiation
GO:0040014  regulation of multicellular organism growth
GO:0019218  regulation of steroid metabolic process
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006105  succinate metabolic process
GO:0033077  T cell differentiation in the thymus
GO:0043029  T cell homeostasis
GO:0019530  taurine metabolic process
GO:0006351  transcription, DNA-dependent
GO:0006573  valine metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005509  calcium ion binding
GO:0005515  protein binding
GO:0004871  signal transducer activity
GO:0003700  transcription factor activity