tachykinin receptor 1

Synonym

TAC1R, NK1R, TACR1, NK-1R, NK-1 receptor, Substance-P receptor, Substance P receptor (SPR), tachykinin receptor 1, Tachykinin receptor 1, NKIR, SPR

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

nodata

CAGE

cerebrum:1.37

cerebellum:-

brain stem:0.39

corpus callosum/glia:0.59

pineal gland:0.43

peripheral nerve:-

spine:0.94

retina:-

eye:-

artery/aorta:1.88

vein:1.92

lymphnode:1.85

peripheral blood:-

spleen:0.09

thymus:0.64

bone marrow:-

adipose:3.59

bone:-

skin:-

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:9.30

salivary:-

GeneChip

nodata

CAGE

uterus:3.36

placenta:1.37

prostate:2.42

ovary:2.02

testis:0.89

heart:1.03

muscle:0.85

esophagus:2.17

stomach:-

intestine:1.33

colon:1.28

liver/hepato:0.36

lung:1.21

bladder:2.20

kidney:1.03

pituitary:0.63

thyroid/parathyroid:1.07

adrenal gland:-

pancreas:0.58

breast:2.02

salivary:1.15

RNA-seq

nodata

IDs

Refseq ID	NM_001058000
Gene ID	6869
Unigene ID	Hs.633301
Probe set ID	-
Ensembl ID	-
GTEx ID	-

Orthologous Gene

Mouse [0]
Rat [0]

Chromosomal Region

2p12 [75,276,231 - 75,426,826]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily
IPR000046	Neurokinin NK1 receptor
IPR001013	Neurokinin NK3 receptor
IPR001681	Neurokinin receptor
IPR000611	Neuropeptide Y receptor

Gene Ontology (GO ID)

Biological Process

GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0002526	acute inflammatory response
GO:0002118	aggressive behavior
GO:0003051	angiotensin-mediated drinking behavior
GO:0008306	associative learning
GO:0007610	behavior
GO:0048266	behavioral response to pain
GO:0009582	detection of abiotic stimulus
GO:0042755	eating behavior
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0006954	inflammatory response
GO:0007616	long-term memory
GO:0007638	mechanosensory behavior
GO:0035106	operant conditioning
GO:0045760	positive regulation of action potential
GO:0045777	positive regulation of blood pressure
GO:0010634	positive regulation of epithelial cell migration
GO:0050679	positive regulation of epithelial cell proliferation
GO:0046887	positive regulation of hormone secretion
GO:0002687	positive regulation of leukocyte migration
GO:0050671	positive regulation of lymphocyte proliferation
GO:0046878	positive regulation of saliva secretion
GO:0051496	positive regulation of stress fiber formation
GO:0032224	positive regulation of synaptic transmission, cholinergic
GO:0032230	positive regulation of synaptic transmission, GABAergic
GO:0070474	positive regulation of uterine smooth muscle contraction
GO:0043117	positive regulation of vascular permeability
GO:0045907	positive regulation of vasoconstriction
GO:0014910	regulation of smooth muscle cell migration
GO:0048660	regulation of smooth muscle cell proliferation
GO:0010996	response to auditory stimulus
GO:0032355	response to estradiol stimulus
GO:0045471	response to ethanol
GO:0009408	response to heat
GO:0043278	response to morphine
GO:0035094	response to nicotine
GO:0010193	response to ozone
GO:0032570	response to progesterone stimulus
GO:0060083	smooth muscle contraction involved in micturition
GO:0042713	sperm ejaculation
GO:0007217	tachykinin receptor signaling pathway

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005515	protein binding
GO:0016496	substance P receptor activity
GO:0004995	tachykinin receptor activity

tachykinin receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function